BÁO CÁO CA BỆNH: NẤM DA DO TRICHOPHYTON INDOTINEAE ĐẦU TIÊN TẠI MIỀN BẮC VIỆT NAM

Abstract

Dermatophytosis is one of the most commonly seen skin diseases caused by fungi which belong to three genus: Trichophyton, Epidermophyton, and Microsporum. Trichophyton indotineae is a newly identified dermatophyte species with significant resistance to terbinafine, and it has been reported in various countries across Asia, Europe, and North America. In this article, we report the first case of Tinea corporis in Northern Vietnam caused by T. indotineae in a 39-year-old female who had gone for a medical examination at Military Hospital 103. The patient exhibited characteristic lesions, and both microscopic examination and culture technique showed the result that dermatophyte was the causative agent. The isolated fungal strain was identified as T. indotineae through DNA sequencing based on the ITS1-5.8S-ITS2 target. The patient was successfully treated with a combination of oral itraconazole and topical ketoconazole. This case highlights the importance of combining clinical observations with morphological examinations for the diagnosis of fungal skin infections. Additionally, the application of molecular tools for precise identification of the causative agent is crucial for selecting appropriate treatment and supplementing epidemiological information on newly identified dermatophytes species in Vietnam.