THE MORTALITY PROGNOSTIC VALUE OF NEUTROPHIL/LYMPHOCYTE RATIO IN POLYTRAUMA PATIENTS
Main Article Content
Abstract
Objectives: To describe clinical characteristics and assess the mortality prognostic value of the neutrophil/lymphocyte ratio in polytrauma patients. Methods: A prospective, descriptive, longitudinal study on 44 polytrauma patients who were treated at Military Hospital 103 from 01/2020 to 3/2023. The level of consciousness was evaluated according to the Glasgow coma scale, and the injury severity was evaluated using the ISS scale. The neutrophil-lymphocyte ratio was calculated at the time of admission. Results: The majority of polytrauma patients were male (81.82%), aged between 23 and 61, with the main cause being traffic accidents (86.36%). GCS scores were higher in the survival group compared to the deceased group. ISS and NLR T0 scores were lower in the survival group compared to the deceased group. At the time of admission, the NLR value had a prognostic value for polytrauma patient mortality at a moderate level, with p = 0.037 and AUC = 0.69. The cut-off value of NLR at T0 was 7.02, with the sensitivity (Se) and specificity (Sp) values being 0.667 and 0.706, respectively. Conclusion: Most polytrauma patients were male, of working age, with traffic accidents being the leading cause. The NLR value at the time of admission had a significant prognostic value for mortality in polytrauma patients.
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Keywords
Polytrauma, Neutrophil/lymphocyte ratio
References
2. H Fouladseresht, S Bolandparvaz, HR Abbasi, et al. The neutrophil-to- lymphocyte ratio at the time of admission: A new prognostic indicator for hospital mortality of trauma patients. Iran J Allergy Asthma Immunol. 2021; 20(1):33-45.
3. HC Pape, R Lefering, N Butcher, et al. The definition of polytrauma revisited: An international consensus process and proposal of the new 'Berlin definition'. J Trauma Acute Care Surg, 2014; 77(5):780-786.
4. Phạm Thị Ngọc Thảo, Tôn Thanh Trà, Lê Minh Khôi. Đặc điểm dịch tễ, lâm sàng và một số kết quả cận lâm sàng của bệnh nhân sốc chấn thương vào Khoa Cấp cứu, Bệnh viện Chợ rẫy. Tạp chí Y học Thành phố Hồ Chí Minh. 2016.
5. A Sauaia, FA Moore, EE Moore, et al. Epidemiology of trauma deaths: A reassessment. J Trauma. 1995; 38(2):185-193.
6. W Chen, J Yang, B Li, et al. Neutrophil to lymphocyte ratio as a novel predictor of outcome in patients with severe traumatic brain injury. J Head Trauma Rehabil. 2018; 33(1):e53-e59.
7. Nguyễn Trường Giang. Nghiên cứu giá trị của bảng điểm RTS, ISS, NISS trong phân loại, tiên lượng và điều trị bệnh nhân đa chấn thương. Luận án Tiến sĩ Y học. 2007.
8. A Cap, BJ Hunt. The pathogenesis of traumatic coagulopathy. Anaesthesia. 2015; 70 Suppl 1:96-101, e32-e34.
9. Lamichhanep B, Shrestha S, Banskota B, et al. Serum Lactate: An indicator of morbidity and mortality in polytrauma and multi-trauma patients. Nepal Orthpaedic Association Journal 2011; 2(1):7-13.
10. SE Soulaiman, D Dopa, AT Raad, et al. Cohort retrospective study: The neutrophil to lymphocyte ratio as an independent predictor of outcomes at the presentation of the multi-trauma patient. Int J Emerg Med. 2020; 13(1):5.