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Ngày xuất bản: 28/04/2023
Số lượt xem tóm tắt: 84
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DOI: https://doi.org/10.56535/jmpm.v48i4.253
Số xuất bản
Tập 48 Số 4 (2023): TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ SỐ 4 - 2023
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Bài báo
Trích dẫn bài báo
Le, T. D., Luu, T. B., & Nguyen, M. N. (2023). EFFICACY OF PLATELET-RICH PLASMA INTRA-ARTICULAR INJECTION IN ADJUNCTION TO CONVENTIONAL THERAPY FOR ASEPTIC NECROSIS OF FEMORAL HEAD. Tạp chí Y Dược học Quân sự, 48(4), 160-171. https://doi.org/10.56535/jmpm.v48i4.253

EFFICACY OF PLATELET-RICH PLASMA INTRA-ARTICULAR INJECTION IN ADJUNCTION TO CONVENTIONAL THERAPY FOR ASEPTIC NECROSIS OF FEMORAL HEAD

Le Thuy Duong1, , Luu Thi Binh2, Nguyen Minh Nui3
1 Hai Phong Medical College
2 Thai Nguyen Province Health Department
3 Vietnam Military Medical University

Nội dung chính của bài viết

Tóm tắt

Objectives: To evaluate the results of autologous platelet-rich plasma (PRP) intra-articular injection combined with medical therapy in treating aseptic necrosis of the femoral head (ANFH) after 5 months. Subjects and methods: Non-control interventional study, comparing before and after treatment for 30 patients (47 sterile necrotic femoral heads) who received 2 injections of PRP one month apart. Evaluation of clinical symptoms and images of necrosis on magnetic resonance imaging of the hip joint after 5 months. Results: The mean Visual Analogue Scale (VAS) decreased from 7.03 ± 1.90 to 3.77 ± 2.64, and the rate of severe pain decreased from 63.3% to 23.3%. The average range of motion of the hip joint increased (flexion from 87.17 ± 13.69 to 101.50 ± 14.69; abduction from 21.50 ± 5.89 to 28.50 ± 7.09; external rotation from 28.33 ± 4.01 to 34.00 ± 5.15; internal rotation from 30.33 ± 4.90 to 34.17 ± 4.93 degrees) with p < 0.001. According to Merle D'Aubigné, the ability to walk score increased from 4.05 ± 0.83 to 4.95 ± 0.76 (p < 0.001). Magnetic resonance imaging showed the rate of bone marrow edema decreased from 66.7% to 40.0% (p < 0.05), four sterile necrotic femoral heads from stage III to stage IV. Conclusion: The results of autologous PRP intra-articular injection combined with medical therapy in treating ANFH have markedly improved analgesia and motor function.

Chi tiết bài viết

Author Biographies

Luu Thi Binh, Thai Nguyen Province Health Department

Từng là Trưởng khoa Cơ xương khớp bệnh viện Trung ương Thái Nguyên, giảng viên Bộ môn Nội trường Đại học Y dược - Đại học Thái Nguyên. Hiện tại là Phó Giám đốc Sở Y tế tỉnh Thái Nguyên

Nguyen Minh Nui, Vietnam Military Medical University

Phó trưởng Bộ môn Khớp- Nội tiết, Học viên Quân Y

Từ khóa

Aseptic necrosis of the femoral head, Platelet-rich plasma

Tài liệu tham khảo

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