NGHIÊN CỨU THÀNH PHẦN HÓA HỌC VÀ TÁC DỤNG KHÁNG VI SINH VẬT IN VITRO CỦA TINH DẦU TỪ PHẦN TRÊN MẶT ĐẤT CÂY CÙ ĐÈN CỬU LONG (Croton kongensis Gagnep.)

Abstract

Background & Objectives: Our study aimed to investigate the chemical composition and antimicrobial activity of essential oils from aerial part of Croton kongensis, that collected in Hoa Binh province. Methods: The essential oils from aerial part of Croton kongensis was isolated using the steam distillation method. The essential oils composition was analyzed by GC-MS while the antimicrobial activity of the essential oils was evaluated by micro dilution method. Results: GC-MS analysis led to the identification of fifty-six components, accounting for 98.65% of total oils. Among them, sabinene (32.69%), germacrene B (9.39%), 2-Isopropyl-5-methyl-(2E)-hexenal (7.52%) and β-elemenone (6.68%) were ascendant in the oils. The antimicrobial assay showed that essential oils from aerial parts of Croton kongensis possessed antimicrobial activity against S. aureus (Both of MSSA and MRSA) and C. albicans while the essential oils were almost ineffective against E. coli and P. aeruginosa up to a concentration of 32 µL/mL. Conclusions: The essential oils from aerial parts of Croton kongensis can be a promising source of sabinene and natural antibacterial for the development of new naturally derived compounds.