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Date Published: 06/10/2024
Abstract Views: 4
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DOI: https://doi.org/10.56535/jmpm.v49si1.946
Issue
Vol. 49 No. si1 (2024): TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ - SỐ ĐẶC BIỆT 10/2024
Section
Hội nghị Khoa học Ghép tạng toàn quốc lần thứ IX
How to Cite
Nguyen, T. T. H., Bui Van Manh, & Le Viet Thang, L. V. T. (2024). DE NOVO HLA - DSA IN PATIENTS WITH KIDNEY FUNCTION REDUCTION IN THE FIRST 6 MONTHS AFTER TRANSPLANTATION. Journal of Military Pharmaco-medicine, 49(si1), 84-92. https://doi.org/10.56535/jmpm.v49si1.946

DE NOVO HLA - DSA IN PATIENTS WITH KIDNEY FUNCTION REDUCTION IN THE FIRST 6 MONTHS AFTER TRANSPLANTATION

Nguyen Thi Thu Ha1, , Bui Van Manh 1, Le Viet Thang Le Viet Thang1
1 Học viện Quân y

Main Article Content

Abstract

Objectives: Survey characteristics of de novo HLA - DSA and study of the relationship with some clinical and paraclinical characteristics in patients with reduced kidney function in the first 6 months after transplantation. Methods: Prospective, cross-sectional, follow-up after transplantation. Results: The incidence of de novo HLA - DSA after kidney transplantation was 33.3% (with a mean MFI of 1442). The level of HLA compatibility < 3/6 was associated with de novo HLA-DSA after transplantation (p < 0.05). The occurrence of proteinuria after kidney transplantation was associated with a 22-fold higher risk of de novo HLA-DSA (OR = 22.25; p < 0.05). Conclusion:  The ratio of de novo HLA - DSA appearing after transplantation in patients with reduced kidney function is high. The low level of HLA compatibility and the appearance of proteinuria after transplantation are related to the appearance of de novo HLA – DSA.

Article Details

Keywords

HLA – DSA, Kidney function reduction, The first months after transplantation.

References

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