GIÁ TRỊ CỦA CÁC DẤU HIỆU KÍCH THƯỚC, ĐỘ SÂU VÀ TÍN HIỆU TRÊN CHUỖI XUNG T2W CỦA CỘNG HƯỞNG TỪ TRONG CHẨN ĐOÁN PHÂN BIỆT KHỐI U PHẦN MỀM LÀNH TÍNH VÀ ÁC TÍNH

Abstract

Objectives: To evaluate the value of size, depth, and signal intensity on T2-weighted magnetic resonance imaging (MRI) in the differential diagnosis of benign and malignant soft tissue tumors. Methods: A retrospective, cross-sectional descriptive study on 112 patients with histopathological diagnosis of soft tissue tumors (62 benign, 50 malignant). On MRI, three signs of size (≤ 50mm, > 50mm), depth (superficial or deep) and T2-weighted signal (homogeneous or heterogeneous) were analyzed to determine the ability to predict the benign or malignant soft tissue tumor. Results: Univariate and multivariate analysis showed that size (p = 0.002) and signal heterogeneity on T2W (p = 0.001) were statistically significant different between benign and malignant soft tissue tumors. Depth was not a valuable independent factor in distinguishing these two tumor groups (p = 0.307). The combination of two signs: Size and heterogeneous signal on T2W is useful in differentiating between benign and malignant soft tissue tumors with a sensitivity of 66%, a specificity of 79%, a positive predictive value of 72%, a negative predictive value of 74% and an accuracy of 75%. Conclusion: The combination of two signs: Size and heterogeneous signal on T2WI is useful in differentiating between benign and malignant soft tissue tumors with a sensitivity of 66%, a specificity of 79%, a positive predictive value of 72%, a negative predictive value of 74%, and an accuracy of 75%.