MỘT SỐ ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG LIÊN QUAN ĐẾN MỨC ĐỘ NẶNG CỦA BỆNH NHÂN NHI TỪ 1 THÁNG ĐẾN 15 TUỔI MẮC SỐT XUẤT HUYẾT DENGUE

Abstract

Objectives: To study clinical and paraclinical presentations relating to the severity of pediatric patients from 1 month to 15 years old with Dengue hemorrhagic fever (DHF). Subjects and methods: A retrospective, cross-sectional descriptive study on 81 patients diagnosed with Dengue hemorrhagic fever in the Pediatrics Department of Military Hospital 103 - Vietnam Military Medical University, from January 2022 to January 2023. Results: 31/80 (38.27%) children with dengue shock (DS). Percentage of overweight and obese children in the shock group 11/31 (35.48%, p < 0.05) and a history of dengue 29/31 (93.5%, p < 0.05). Some symptoms are predominantly found in DS group: abdominal pain (93.55%, p < 0.05), nausea and vomiting (90.32%, p < 0.05), gastrointestinal hemorrhage and melena (9.68%, p < 0.05), hepatomegaly (67.74%, p < 0.05), oliguria (83.87%, p < 0.05). Subclinical in DS group:  Hct > 0.45 L/L (19/31 (61.29%),          p < 0.05), WBC over 4 G/L (21/31 (67.74%), p < 0.05), neutrophil percentage (34.6 ± 11.5%) platelet count < 20 G/L (19/31 (61.29%), increase in AST levels (405 ± 408 U/L, p < 0.01) and decrease in albumin (27.2 ± 4.64 g/L, p < 0.01) and protein levels (52.77 ± 8.62 g/L, p < 0.05), pleural effusion and ascites are common in shock patients (28/31 (93.32%), p < 0,05). Conclusion: Children who are overweight or obese have a history of DF and show symptoms of abdominal pain, nausea and vomiting, gastrointestinal hemorrhage, melena, hepatomegaly, and oliguria related to the severity of the disease. Subclinical symptoms: Hct > 0.45 L/L, platelet count < 20 G/L, increased ASL enzyme, hypoalbuminemia, hypoproteinemia, pleural effusion, and ascites are factors related to the severity of patients with DHF