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STUDY ON CLINICAL CHARACTERISTICS AND PREDICTORS OF SEVERITY OF DENGUE FEVER CHILDREN
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Abstract
Objectives: To evaluate clinical data and warning signs of children infected with Dengue hemorrhagic fever (DHF). Subjects and methods: A retrospective, cross-sectional descriptive study on 81 patients diagnosed with DHF in the Pediatrics Department of Military Hospital 103 - Vietnam Military Medical University, from January 2022 to January 2023. Results: The age group from 6 to 10 were found to have a greater risk of acquiring DHF; overweight children were identified as having a relation with the severity of the disease (p < 0.05), Dengue fever patients having shock experienced higher temperature febrile than the group without shock (p < 0.05). There is no difference between patients with shock and without shock in some symptoms recorded: Headache, pain behind the eyes, myalgia (92% versus 93.55%; p > 0.05), petechiae (90% versus 93.55%, p > 0.05). Otherwise, changes in mental status such as agitation, lethargy or unconsciousness (96.77%, p < 0.05), nausea, vomiting (90.32%, p < 0.05), abdominal pain (93.55%, p < 0.05), epistaxis (54.84%, p < 0,05), gastrointestinal hemorrhage (96.8%, p < 0.05), hepatomegaly (67.74%, p < 0,05) are remarkable higher in patients having shock comparing to the remaining group. A decrease in urine output and cool clammy extremities are more likely to be encountered in the shock group (83.87%, p < 0.05). Systolic blood pressure in the shock group is generally lower than in the non-shock group (p < 0.05). Furthermore, the shock group has the tendency to be higher in terms of heart rate (p < 0.01) and refill capillary time (p < 0.01) compared to the non-shock group, while the blood oxygen saturation in the shock group is lower than its counterpart. Conclusion: Obesity, hyperpyrexia, abdominal pain, nausea, excessive vomiting, epistaxis, and gastrointestinal hemorrhage resulting in melena and hepatomegaly are markers of severe disease, and pre-shock state symptoms are meaningful to the evaluation of the patient’s severity.
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Keywords
Dengue fever, Warning signs, Risk factor, Children, Shock
References
2. Cục Y tế Dự phòng. 2019. Bộ Y tế. Báo cáo cập nhật tình sốt xuất huyết Dengue.
3. Bộ Y tế. Hướng dẫn chẩn đoán, điều trị sốt xuất huyết Dengue. Nhà xuất bản Y học. 2019.
4. Pham Thanh Binh., et al. 2007. Predictive factors of dengue shock syndrome at the children Hospital No. 1, Ho-Chi-Minh City, Vietnam. Bull Soc Pathol Exot; 100(1): 43-47.
5. Harris, E., et al., 2000. Clinical, epidemiologic, and virologic features of dengue in the 1998 epidemic in Nicaragua. The American Journal of Tropical Medicine and Hygiene; 63(1): 5-11.
6. Gupta, V., et al., 2011. Risk factors of dengue shock syndrome in children. J Trop Pediatr; 57(6): 451-456.
7. Narayanan, M., et al., 2002. Dengue fever epidemic in Chennai: A study of clinical profile and outcome. Indian Pediatr; 39(11): 1027-1033.
8. Kalayanarooj, S. and S. Nimmannitya. 2005. Is dengue severity related to nutritional status? Southeast Asian J Trop Med Public Health; 36(2): 378-384.
9. Gayatri, P., 1997. Faktor-faktor prognosis pada demam berdarah dengue [thesis]. Jakarta: University of Indonesia.
10. Giraldo, D., et al., 2011. Characteristics of children hospitalized with dengue fever in an outbreak in Rio de Janeiro, Brazil. Transactions of The Royal Society of Tropical Medicine and Hygiene; 105(10): 601-603.
11. Méndez, A. and G. González. 2003. Dengue haemorrhagic fever in children: Ten years of clinical experience. Biomedica; 23(2): 180-193.
12. Shah, G., S. Islam, and B. Das. 2006. Clinical and laboratory profile of dengue infection in children. Kathmandu University Medical Journal (KUMJ); 4(1): 40-43.