ĐẶC ĐIỂM VÔI HOÁ VÀ HẸP MẠCH VÀNH TRÊN HÌNH ẢNH CẮT LỚP VI TÍNH 256 DÃY Ở BỆNH NHÂN TĂNG HUYẾT ÁP

Abstract

Objectives: To study the characteristics of coronary artery calcification (CAC) and stenosis (CAS) on 256-slice CT-scan (MSCT-256) in hypertensive patients. Subjects and methods: A cross-sectional descriptive study of the coronary artery imaging characteristics on 256 slices MSCT in hypertensive patients at Viet Duc University Hospital from February to July 2021. Results: There were 269 patients (129 male and 140 female) with a mean age of 72.6 ± 10.5 years (ranging from 41 to 90 years). CAC was found in 97 males (75.2%) and 90 females (64.3%) (p = 0.05). The prevalence of CAC in over 60-year-old patients was significantly higher than in those £ 60 years old (72.2% vs. 51.4%; p =0.01). Regarding CAS, the median age of patients with < 50% CAS was significantly lower than that of patients with ³ 50%-CAS (72 vs. 76 years; p < 0.01). Moreover, patients aged > 60 had a higher risk of ³ 50% CAS than those aged £ 60 (OR: 5.9; 95%CI: 1.4 - 25.6; p < 0.01). The Agatston score was significantly lower in patients with < 50% CAS than in those with ³ 50% CAS (23 vs. 329; p < 0,01). Patients with CAC had a higher risk of having ³ 50% CAS than those without CAC (OR: 6.6; 95%CI: 2.5 - 17.1; p < 0.01), and those with severe CAC (> 400 Agatston score) had a higher risk than those with mild or no CAC (OR: 17.3; 95%CI: 8.4 - 51.9; p < 0,01). The ROC curve for predicting Agatston score with ³ 50% CAS had an AUC of 0.824, with a cut-off score of 104 with a sensitivity of 77% and specificity of 76%. Conclusion: High Agatston score and old age are factors positively correlate with severe coronary artery stenosis in hypertensive patients.