SỰ THAY ĐỔI CHỈ SỐ DINH DƯỠNG TIÊN LƯỢNG Ở NGƯỜI BỆNH TRƯỚC VÀ SAU GHÉP THẬN TẠI BỆNH VIỆN QUÂN Y 103

Abstract

Objectives: To evaluate changes in the prognostic nutritional index (PNI) before and after kidney transplantation and to investigate its association with selected clinical and paraclinical characteristics during the first 3 months after transplantation. Methods: A longitudinal descriptive study without a control group was conducted on 101 kidney transplant recipients at Military Hospital 103 from July 2025 to July 2026. Laboratory tests were performed immediately before transplantation (T0) and at 3 months after transplantation (T3), and post-transplant events were monitored during the first 3 months after transplantation. Results: PNI increased from 48.79 ± 5.45 at T0 to 52.27 ± 4.93 at T3. PNI (T3) was lower in patients aged ≥ 40 years, receiving ATG, with anemia at T3, with infections during the first 3 months after transplantation, and those with an eGFR < 60 mL/min/1.73m². PNI at T3 < 50 was associated with higher OR of anemia at T3 and post-transplant infection, with an OR of 3.96 and 4.14, respectively. When PNI was analyzed as a continuous variable, each 1-point increase in post-transplant PNI was associated with a 21% reduction in the odds of anemia and a 16% reduction in the odds of infection. Conclusion: Post-transplant PNI (T3) improved significantly and was associated with age, induction therapy, and several early post-transplant events, including anemia and infection.