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Issue: Vol. 51 No. 9 (2026): JOURNAL OF MILITARY PHARMACO-MEDICINE No.9 - 2026
Section: Articles
DOI: 10.56535/jmpm.v51i9.2142
Date Published: 28/09/2026
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Le, N. D., Nguyen, T. P. T., & Bui, H. B. (2026). ASSOCIATION BETWEEN GENERALIZED PAIN HYPERSENSITIVITY, DISEASE ACTIVITY, AND FUNCTIONAL DISABILITY IN RHEUMATOID ARTHRITIS. Journal of Military Pharmaco-medicine, 51(9), 86-93. https://doi.org/10.56535/jmpm.v51i9.2142

ASSOCIATION BETWEEN GENERALIZED PAIN HYPERSENSITIVITY, DISEASE ACTIVITY, AND FUNCTIONAL DISABILITY IN RHEUMATOID ARTHRITIS

Ngoc Diep Le1, , Thi Phuong Thuy Nguyen1,2, Hai Binh Bui2
1 Hanoi Medical University
2 Bach Mai Hospital

Main Article Content

Abstract

Objectives: To describe generalized pain hypersensitivity in the study population using the Generalized Pain Questionnaire (GPQ) and to investigate its association with disease activity and functional disability. Methods: A cross-sectional descriptive study was conducted on 81 patients diagnosed with rheumatoid arthritis according to the ACR/EULAR 2010 criteria who were receiving treatment at the Centre for Rheumatology, Bach Mai Hospital, from November 2025 to March 2026. Results: The prevalence of generalized pain hypersensitivity among the study participants, as assessed using the GPQ, was 17.3% (14/81 patients). This group of patients was younger, exhibited higher disease activity, required more frequent corticosteroid use, and had higher Health Assessment Questionnaire Disability Index (HAQ-DI) scores. All associations were statistically significant. Conclusion: Early screening for generalized pain hypersensitivity is very important in pain assessment and treatment orientation to improve patients’ quality of life.

Keywords

Rheumatoid arthritis, Generalized pain, Functional disability, Generalized Pain Questionnaire

Article Details

References

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