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Issue: Vol. 51 No. 7 (2026): JOURNAL OF MILITARY PHARMACO-MEDICINE No.7 - 2026
Section: Articles
DOI: 10.56535/jmpm.v51i7.2061
Date Published: 28/07/2026
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Nguyen, T. T. H., Pham, Q. T., Nguyen, T. T., & Diem, T. V. (2026). EVALUATION OF CHANGES IN PRURITUS STATUS ACCORDING TO THE 5-D ITCH SCALE IN MAINTENANCE HEMODIALYSIS PATIENTS BEFORE AND AFTER AN ONLINE HEMODIAFILTRATION SESSION. Journal of Military Pharmaco-medicine, 51(7), 142-151. https://doi.org/10.56535/jmpm.v51i7.2061

EVALUATION OF CHANGES IN PRURITUS STATUS ACCORDING TO THE 5-D ITCH SCALE IN MAINTENANCE HEMODIALYSIS PATIENTS BEFORE AND AFTER AN ONLINE HEMODIAFILTRATION SESSION

Thi Thu Ha Nguyen1, Quoc Toan Pham1, Thi Trang Nguyen1, Thi Van Diem1,
1 Military Hospital 103

Main Article Content

Abstract

Objectives: To investigate changes in pruritus status according to the 5-D itch scale  in  maintenance  hemodialysis  (MHD)  patients  before  and  after  an  online hemodiafiltration (OL-HDF) session. Methods: A prospective, uncontrolled, before-and-after intervention study was conducted on 74 maintenance hemodialysis patients at the Department of Nephrology and Dialysis, Military Hospital 103, from June 2025 to April 2026. Pruritus symptoms were assessed using the 5-D itch scale before the OL-HDF session, as well as 2 weeks and 4 weeks after the session. Baseline hematological and biochemical tests were performed before the OL-HDF session. Results: The prevalence of pruritus was 83.8%, with a mean 5-D score of 11.5 ± 3.94, which was predominantly mild to moderate. At 2 weeks post-OL-HDF session, both the individual components and the total 5-D itch score demonstrated the most significant improvement. After 4 weeks, the 5-D itch score remained lower than baseline (before the OL-HDF session) but was higher than the score at 2 weeks. Conclusion: Pruritus is a highly prevalent symptom in MHD patients. OL-HDF is an effective hemodialysis method that alleviates pruritus in MHD patients; however, the effectiveness of this method decreases over time

Keywords

CKD, Hemodialysis, OL-HDF, Itching, 5-D itch scale

Article Details

References

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