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Issue: Vol. 51 No. 6 (2026): JOURNAL OF MILITARY PHARMACO-MEDICINE No.6 - 2026
Section: Articles
DOI: 10.56535/jmpm.v51i6.2031
Date Published: 28/06/2026
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How to Cite
Quan, T. N., Do, L. H., Nghiem, D. T., Nguyen, P. L., Do, V. T., Do, T. S., Ngo, D. T., Ngo, T. H., Luu, D. P., Ngo, M. Q., & Nguyen, T. P. (2026). DIAGNOSTIC VALUE OF EOSINOPHIL COUNT IN PATIENTS WITH CHRONIC RHINOSINUSITIS WITH NASAL POLYPS. Journal of Military Pharmaco-medicine, 51(6), 214-223. https://doi.org/10.56535/jmpm.v51i6.2031

DIAGNOSTIC VALUE OF EOSINOPHIL COUNT IN PATIENTS WITH CHRONIC RHINOSINUSITIS WITH NASAL POLYPS

Thanh Nam Quan1, Lan Huong Do1, , Duc Thuan Nghiem1,2, Phi Long Nguyen1, Van Tung Do3, Thai Son Do4, Duc Thang Ngo2, Thi Huong Ngo2, Dac Phong Luu2, Minh Quan Ngo2, Thanh Pham Nguyen2
1 Military Hospital 103
2 Vietnam Military Medical University
3 7 Military Hospital
4 Phuong Dong General Hospital

Main Article Content

Abstract

Objectives: To determine the diagnostic value of eosinophil count in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Methods: A descriptive study was conducted on 84 patients diagnosed with CRSwNP and treated at the Department of Otorhinolaryngology, Military Hospital 103, from January 2022 to May 2025. Results: Tissue eosinophil count showed a high diagnostic value in classifying inflammatory severity in patients with CRSwNP (AUC > 0.8; p < 0.001), with an optimal cut-off value of 67.5 eosinophils/high-power field (HPF), sensitivity of 93.8% and specificity of 86.5%. Patients with predominant tissue eosinophilia had significantly higher mean Lund-Kennedy scores (9.12 ± 2.76 and 7.46 ± 3.12) and Lund-Mackay scores (18.02 ± 3.67 and 14.04 ± 4.65) compared to those without tissue eosinophilia (p < 0.05). In contrast, peripheral blood eosinophil percentage showed poor diagnostic value and was not statistically significant. Conclusion: A threshold of 67.5 eosinophils/HPF in polyp tissue is a valuable marker for assessing inflammatory severity and is associated with endoscopic and computed tomography severity, highlighting its potential to be combined with these factors for prognostic classification and treatment in CRSwNP.

Keywords

Eosinophilia, Inflammatory severity, Chronic rhinosinusitis with nasal polyps

Article Details

References

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