OUTCOMES OF MINI-PERCUTANEOUS NEPHROLITHOTOMY OF KIDNEY STONES WITH STABILIZED URINARY TRACT INFECTION AT THAI NGUYEN NATIONAL HOSPITAL
Main Article Content
Abstract
Objectives: To evaluate the results of mini percutaneous nephrolithotomy (mini-PCNL) for the treatment of kidney stones with stabilized urinary tract infection. Methods: A descriptive study was conducted on 40 patients who underwent surgery at Thai Nguyen National Hospital from January 2024 to March 2025. Results: Mean stone size was 42.1 ± 18.6mm. According to the Guy’s Stone score, grade II accounted for 66.7%, while grades III and IV accounted for 16.7% and 9.5%. Escherichia coli was the most common causative pathogen of urinary tract infections. Multidrug-resistant bacteriuria was identified in 32.5% of patients. The median duration of preoperative antibiotic therapy was 6.5 days. The stone-free rate was 69%. Overall complication rate was 17.5%, including postoperative fever (2.4%), systemic inflammatory response syndrome (7.1%), septic shock (2.4%), and bleeding requiring blood transfusion 4.8%. The median postoperative treatment time was 5 days. Conclusion: Mini percutaneous nephrolithotomy is an effective and relatively safe method for treating kidney stones with controlled urinary tract infections, achieving a rate of 69% and a postoperative complication rate of 17.5%. Preoperatively, a stone-free management of urinary tract infections plays a critical role in reducing the risk of postoperative infectious complications.
Keywords
Kidney stone, Urinary tract infection, Mini-percutaneous nephrolithotomy
Article Details
References
2. Sutibud K, Kitirattrakarn P, & Saengmearnuparp T. Clinical outcomes and complications of percutaneous nephrolithotomy (PCNL) in multidrug resistant (MDR) bacteriuria. Insight Urology. 2024; 45(2):73-79. https://doi.org/ 10.52786/isu.a.88.
3. Xu P, Zhang S, Zhang Y, et al. Preoperative antibiotic therapy exceeding 7 days can minimize infectious complications after percutaneous nephrolithotomy in patients with positive urine culture. World J Urol. 2022; 40(1):193-199. DOI:10.1007/s00345-021-03834-y.
4. Jiao B, Luo Z, Huang T, Zhang G, Yu J. A systematic review and meta-analysis of minimally invasive vs. standard percutaneous nephrolithotomy in the surgical management of renal stones. Exp Ther Med. 2021; 21(3):213. DOI:10.3892/etm.2021.9645.
5. Danilovic A, Dias LPC, Torricelli FCM, et al. High-risk patients for septic shock after percutaneous nephrolithotomy.
Int Braz J Urol. 2024; 50(5):561-571. DOI:10.1590/S1677-5538.IBJU.2024.0154.
6. Sur RL, Krambeck AE, Large T, et al. A randomized controlled trial of preoperative prophylactic antibiotics for percutaneous nephrolithotomy in moderate to high infectious risk population: A report from the EDGE consortium.
J Urol. 2021; 205(5):1379-1386. DOI:10.1097/JU.0000000000001582.
7. Yang Z, Lin D, Hong Y, et al. The effect of preoperative urine culture and bacterial species on infection after percutaneous nephrolithotomy for patients with upper urinary tract stones. Sci Rep. 2022; 12(1):4833. Published 2022 Mar 22. DOI:10.1038/s41598-022-08913-7.
8. Gorgotsky I, Shkarupa D, Shkarupa A, Yarova N, Suchkov D. Feasibility of percutaneous nephrolithotomy in positive urine culture: A single center retrospective study. Urol J. 2020; 17(6):587-591. Published 2020 Apr 19. DOI:10.22037/uj.v0i0.5561.
9. Lê Đình Vũ, Trương Thanh Tùng, Nguyễn Anh Lương và CS. Kết quả tán sỏi qua da đường hầm nhỏ tại Bệnh viện Đa khoa tỉnh Thanh Hoá qua 300 trường hợp. Y học TP Hồ Chí Minh. 2019; 23 (3):78-84.