EVALUATION OF POSTOPERATIVE CRITICAL CARE OUTCOMES AFTER LIVING-DONOR KIDNEY TRANSPLANTATION AT MILITARY HOSPITAL 175

Quách Tuấn Anh Phạm1, , Quoc Viet Tran1, Viet Cuong Nguyen1, Ngoc Phat Ho1, Minh Tu Duong1, Thi Cam Vi Ho1, Viet Tinh Luu1, Tan Phu Nghiem1
1 Bệnh viện Quân y 175

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Abstract

Objectives: To describe clinical and paraclinical characteristics and to evaluate complications during postoperative critical care after living donor kidney transplantation at Military Hospital 175. Methods: A retrospective, descriptive study was conducted on 50 patients who underwent living donor kidney transplantation at the Surgical ICU of Military Hospital 175, including patients ≥ 18 years who underwent kidney transplantation from July 2023 to June 2025. Results: the mean age was 42.3 ± 12.1 years; 68% patients were male; the mean BMI was 21.35 ± 2.52 kg/m². Most patients had chronic comorbidities and prolonged pre-transplant dialysis. No severe respiratory complications occurred postoperatively. Vasopressor support was required in 2% of cases. Hypertension requiring treatment was observed in 86% of cases. Early postoperative polyuria and electrolyte disturbances occurred but resolved quickly; serum urea and creatinine levels approached near-normal values by day 3. Complications were observed in 12% of patients (n = 6), including postoperative bleeding requiring reoperation (n = 2), lymphocele (n = 2), and acute rejection (n = 2). Conclusion: Living donor kidney transplantation carries considerable complication risks during the post-resuscitation period. Close postoperative monitoring is essential for timely detection and intervention to optimize outcomes.

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References

1. Wolfe RA, Ashby VB, Milford EL, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med. 1999; 341(23):1725-1730.
2. Dal Magro PS, Meinerz G, Garcia VD, Mendes FF, Marques MEC, Keitel E. Kidney transplantation and perioperative complications: A prospective cohort study. Front Transplant. 2024; 3:18.
3. Trương Hồ Trọng Tấn. Đánh giá kết quả ghép thận từ người hiến thận sống trong năm đầu sau ghép tại Bệnh viện Chợ Rẫy. Tạp chí Y Dược học Quân sự. Số đặc biệt 10/2024.
4. Abrol N, Kashyap R, Frank RD, et al. Preoperative factors predicting admission to the intensive care unit after kidney transplantation. Mayo Clin Proc Innov Qual Outcomes. 2019; 3:285-293.
5. Canet J, Gallart L, Gomar C, et al. Prediction of postoperative pulmonary complications in a population-based surgical cohort. Anesthesiology. 2016; 125(1):65-75.
6. Kwon H, Kim YH, Choi JY, et al. Analysis of 4000 kidney transplantations in a single center: Across immunological barriers. Medicine (Baltimore). 2016; 95(32):e4249.
7. Hội Ghép tạng Việt Nam. Hướng dẫn Ghép thận Việt Nam. Nhà xuất bản Y học. 2017.
8. Nguyễn Thị Hoa. Nghiên cứu sự thay đổi chỉ số sinh hóa ở bệnh nhân ghép thận điều trị bằng Cyclosporin hoặc Tacrolimus. Luận án Tiến sỹ Y học, Trường Đại học Y Hà Nội. 2012.
9. Nogueira de Sa P, Narayanan M, Lim MAC. Electrolyte and acid-base abnormalities after kidney transplantation. Adv Kidney Dis Health. 2024; 31(5): 450-457.
10. Bùi Văn Mạnh. Nghiên cứu chỉ số lâm sàng, cận lâm sàng và một số yếu tố miễn dịch ở bệnh nhân sau ghép thận. Luận văn Tiến sỹ Y học, Học viện Quân y. 2012.