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Date Published: 10/12/2025
Abstract Views: 34
Views PDF: 18
DOI: 10.56535/jmpm.v50si4.1662
Issue
Vol. 50 No. si4 (2025): JOURNAL OF MILITARY PHARMACO-MEDICINE - SPECIAL ISSUE 12/2025
Section
Special issue celebrating the 75th anniversary of Military Hospital 103
How to Cite
Le, D. M., Nguyen, Q. H., Pham, V. C., Tran, V. T., Vu, D. D., Nguyen, T. G., Nguyen, T. K., & Vu, M. D. (2025). EARLY COAGULOPATHY AND CLINICAL OUTCOMES OF MULTIPLE TRAUMA PATIENTS AT MILITARY HOSPITAL 103. Journal of Military Pharmaco-medicine, 50(si4), 601-608. https://doi.org/10.56535/jmpm.v50si4.1662

EARLY COAGULOPATHY AND CLINICAL OUTCOMES OF MULTIPLE TRAUMA PATIENTS AT MILITARY HOSPITAL 103

Dang Manh Le1, , Quang Huy Nguyen1, Van Cong Pham1, Van Tung Tran1, Dinh Dien Vu1, Truong Giang Nguyen2, Trung Kien Nguyen2, Minh Duong Vu1
1 Bệnh viện Quân y 103, Học viện Quân y
2 Cục Quân y

Main Article Content

Abstract

Objectives: To determine the relationship between early coagulopathy and the treatment outcomes of patients with multiple trauma. Methods: A retrospective, descriptive study was conducted on 196 patients who were admitted to the Surgery Intensive Care Department, Military Hospital 103, from June 2020 to June 2023. Data were collected and analyzed using standard statistical methods. Results: The majority of patients were between 20 - 59 years of age (71.5%), predominantly male (80.1%), with traffic accidents being the leading cause of injury (66.8%). Early coagulopathy was observed in 36.7% of patients with multiple trauma. Compared with those without coagulopathy, patients in the coagulopathy group had significantly higher ISS scores, lower Glasgow Coma Scale scores, and higher 30-day mortality rates. The areas under the receiver operating characteristic curve for predicting mortality were 0.762 for INR, 0.709 for ISS, and 0.683 for aPTT. Conclusion: Early coagulopathy occurred in 36.7% of patients with multiple trauma. Patients in the coagulopathy group had significantly higher ISS scores, lower Glasgow Coma Scale scores, and higher 30-day mortality rates compared with those without coagulopathy. aPTT, INR, and ISS were all significant predictors of mortality in patients with multiple trauma.

Keywords

Coagulopathy, Multiple trauma, Outcome

Article Details

References

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