THỰC TRẠNG NHIỄM KHUẨN ĐƯỜNG TIẾT NIỆU DƯỚI Ở BỆNH NHÂN ĐIỀU TRỊ NỘI TRÚ TẠI KHOA TIẾT NIỆU DƯỚI, BỆNH VIỆN TRUNG ƯƠNG QUÂN ĐỘI 108 TỪ THÁNG 10 - 12/2024

Abstract

Objective: To describe the clinical, microbiological characteristics, and empirical antibiotic treatment regimens in patients diagnosed with lower urinary tract infections (LUTIs) who were hospitalized in the Lower Urinary Tract Department, 108 Military Central Hospital. Methods: A retrospective, cross-sectional descriptive study was conducted by reviewing the medical records of 119 inpatients diagnosed with LUTIs from October to December 2024. Data collected included clinical presentations, laboratory and microbiological findings, and antibiotic regimens administered. Results: Males accounted for 88.2%, females accounted for 11.8%, and the 62 - 78-year age group comprised 46.2%. The most common symptoms were voiding difficulty (51.3%), urinary frequency (42.0%), urinary retention (41.2%), and painful/burning urination (38.7%). Positive urine cultures were found in 58 cases, predominantly E.coli (36.2%) and P.aeruginosa (19.0%). E.coli remained susceptible to amikacin (85.7%) and carbapenems (85.7 - 90%) but showed high resistance to cephalosporins and fluoroquinolones (> 50%). Empirical initial therapy accounted for 81.5%, with cephalosporin monotherapy being the most common regimen (30.9%). Conclusion: Lower urinary tract infections (LUTIs) in this inpatient cohort are predominantly caused by E.coli with substantial resistance to cephalosporins/fluoroquinolones; aminoglycosides or carbapenems should be considered for severe or high-risk cases.