HYPOALBUMINEMIA IN HEMODIALYSIS PATIENTS AGED OVER 60 YEARS AT MILITARY HOSPITAL 103
Main Article Content
Abstract
Objectives: To investigate the prevalence of hypoalbuminemia and its association with selected clinical and paraclinical features in elderly patients with end-stage kidney disease (ESKD) undergoing maintenance hemodialysis. Methods: A prospective, cross-sectional descriptive, uncontrolled study was conducted on 72 maintenance hemodialysis patients aged over 60 years at the Department of Nephrology and Hemodialysis, Military Hospital 103 from June 2023 to June 2024. Results: The prevalence of hypoalbuminemia (serum albumin < 35 g/L) was 18.06%, with a mean albumin level of 38.16 ± 3.27 g/L. Patients with severe anemia (hemoglobin < 80 g/L) had significantly lower albumin levels compared to others (36.81 ± 3.61 vs. 38.71 ± 2.98 g/L; p = 0.023). Likewise, patients who experienced intradialytic hypotension within the past month had significantly lower albumin levels than those without (36.53 ± 2.51 vs. 39.69 ± 3.19 g/L; p < 0.001). A moderate positive correlation was observed between serum albumin and pre-dialysis creatinine levels (r = 0.31; p = 0.008). Conclusion: The prevalence of hypoalbuminemia among elderly hemodialysis patients was relatively high and significantly associated with severe anemia, lower pre-dialysis creatinine levels, and the occurrence of intradialytic hypotension.
Article Details
Keywords
Hemodialysis, Hypoalbuminemia, Intradialytic hypotension
References
2. Avesani CM, Sabatino A, Guerra A, et al. A comparative analysis of nutritional assessment using global leadership initiative on malnutrition versus subjective global assessment and malnutrition inflammation score in maintenance hemodialysis patients. Journal of Renal Nutrition. 2022; 32(4):476-482.
3. Chen J, Wang J, Liu Y, et al. Mortality and associated risk factors between young and elderly maintenance haemodialysis patients: A multicentre retrospective cohort study in China. BMJ Open. 2023; 13:e066675. DOI: 10.1136/bmjopen-2022-066675.
4. Nguyễn Thuỳ Lan, Mai Thị Hiền, Tống Thị Thu Hằng. Khảo sát nồng độ albumin huyết thanh ở bệnh nhân suy thận mạn thận nhân tạo chu kì trên 60 tuổi tại Bệnh viện Hữu Nghị. Tạp chí Y Dược Lâm sàng 108. 2020; 15(7):96-101.
5. Weaving G, Batstone GF, Jones RG. Age and sex variation in serum albumin concentration: An observational study. Annals of Clinical Biochemistry. 2016; 53(1):106-111.
6. Kooman J, Basci A, Pizzarelli F, et al. EBPG guideline on haemodynamic instability. Nephrol Dial Transplant. 2007; 22(2):22-44.
7. Phạm Đức Minh, Lê Việt Thắng, Lê Đức Toàn. Giảm albumin máu và mối liên quan với tình trạng dịch ngoại bào ở 84 bệnh nhân bệnh thận mạn tính giai đoạn cuối lọc máu chu kì. Tạp Chí Y học Quân sự. 2024; 372:37-41. https://doi.org/10.59459/1859-1655/ JMM.470.
8. Kaynar K, Songul Tat T, Ulusoy S, et al. Evaluation of nutritional parameters of hemodialysis patients. Hippokratia. 2012; 16(3):236-240.
9. Al-Etreby EA, El-Aziz AA, El-Waseef O, et al. The association between hypoalbuminemia and intradialytic hypotension in heamodialysis patients. The Egyptian Journal of Hospital Medicine. 2016; 63:185-194.
10. Hamrahian SM, Vilayet S, Herberth J, et al. Prevention of intradialytic hypotension in hemodialysis patients: Current challenges and future prospects. IJNRD. 2023; 16:173-181.