EVALUATION OF TREATMENT OUTCOMES OF NASAL CONTINUOUS POSITIVE AIRWAY PRESSURE IN CHILDREN WITH COMMUNITY-ACQUIRED PNEUMONIA WITH RESPIRATORY FAILURE IN CAN THO IN 2025
Main Article Content
Abstract
Objectives: To evaluate the treatment outcomes of nasal continuous positive airway pressure (NCPAP) in children hospitalized with community-acquired pneumonia (CAP) with respiratory failure. Methods: A descriptive case series study was conducted on 50 children with CAP aged 2 months to 15 years with respiratory failure requiring NCPAP, admitted and treated at Can Tho Children's Hospital from April 2024 to April 2025. Results: The median age of CAP children with respiratory failure receiving NCPAP was 6.5 months, predominantly infants aged 2 - 12 months (62%). Treatment success was achieved in 60% of patients, with 40% experiencing therapeutic failure. Two independent predictors of NCPAP treatment outcome were gender (OR = 7.286; 95%CI: 1.671 - 31.772; p = 0.008) and fever (OR = 0.112; 95%CI: 0.023 - 0.536; p = 0.006). Conclusion: NCPAP demonstrated 60% treatment efficacy in CAP children with respiratory failure, with male gender and fever identified as prognostic factors for treatment failure.
Keywords
Community-acquired pneumonia, Respiratory failure, Nasal continuous positive airway pressure, Children
Article Details
References
2. Hoang VT, Dao TL, Minodier P, et al. Risk factors for severe pneumonia according to WHO 2005 criteria definition among children < 5 years of age in Thai Binh, Vietnam: A case-control study. J Epidemiol Glob Health. 2019; 9(4):274-280.
3. Trần Duy Vũ, Nguyễn Thị Yến, Lê Thị Hồng Hanh. Hiệu quả của thở áp lực dương liên tục qua mũi trong điều trị suy hô hấp cấp ở trẻ em tại Bệnh viện Nhi Trung ương. Tạp chí Y học Việt Nam. 2021; 506(1):145-148.
4. Kostekci YE, Okulu E, Bakirarar B, et al. Nasal continuous positive airway pressure vs. nasal intermittent positive pressure ventilation as initial treatment after birth in extremely preterm infants. Front Pediatr. 2022; 10:870125.
5. Bộ Y tế. Hướng dẫn Xử trí Viêm phổi cộng đồng ở trẻ em. Quyết định số 101/QĐ-BYT ngày 09/01/2014 của Bộ trưởng Bộ Y tế Việt Nam. 2014.
6. World Health Organization. Pneumonia. Pocket book of hospital care for children: Guidelines for the management of common illness with limit resources. 2013. Geneva: 76-87.
7. Kliegman, RM, Stanton BF, Geme JWS, & Schor NF (Eds.). Nelson Textbook of Pediatrics (21st ed.). Elsevier. 2020.
8. Klein SL, Flanagan KL. Sex differences in immune responses. Nature Reviews Immunology. 2016 Oct;16(10):626-638. DOI:10.1038/nri.2016.90.
9. Smith CB, McCulloch TM, Bassiur SJ, et al. Influence of gender and age on upper airway length. Pediatrics. 2007;120(4):e1028.