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Date Published: 07/11/2025
Abstract Views: 4
Views PDF: 1
DOI: 10.56535/jmpm.v50si3.1508
Issue
Vol. 50 No. si3 (2025): JOURNAL OF MILITARY PHARMACO-MEDICINE - SPECIAL ISSUE 11/2025
Section
Hội nghị Khoa học Ghép tạng toàn quốc lần thứ IX - 2025
How to Cite
Nguyễn, M. H., Quan, T. T., Nguyen, V. D., Do, M. H., Vu, K. K., & Le, V. T. (2025). SURVEY OF THE CHARACTERISTICS OF TACROLIMUS TROUGH CONCENTRATIONS IN KIDNEY TRANSPLANT RECIPIENTS OVER ONE YEAR POST-TRANSPLANT AT MILITARY HOSPITAL 103. Journal of Military Pharmaco-medicine, 50(si3), 45-53. https://doi.org/10.56535/jmpm.v50si3.1508

SURVEY OF THE CHARACTERISTICS OF TACROLIMUS TROUGH CONCENTRATIONS IN KIDNEY TRANSPLANT RECIPIENTS OVER ONE YEAR POST-TRANSPLANT AT MILITARY HOSPITAL 103

Minh Hiếu Nguyễn1, , Thi Tam Quan1, Van Duc Nguyen1, Manh Ha Do1, Kim Khanh Vu2, Viet Thang Le1
1 Bệnh viện Quân y 103, Học viện Quân y
2 Bệnh viện Trung ương Quân đội 108

Main Article Content

Abstract

Objectives: To investigate the characteristics of tacrolimus (TAC) trough concentrations (C0) and their associations with selected clinical and laboratory parameters in kidney transplant recipients over one year post-transplantation. Methods: A cross-sectional descriptive study was conducted on 532 kidney transplant recipients over one year post-transplant, all receiving an immunosuppressive regimen containing TAC, from January 2024 to September 2024. Data on TAC dosing, C0, and relevant clinical and laboratory parameters were collected for descriptive analysis and association testing. Results: The proportion achieving target TAC C0 levels was 73.68% (392/532 patients), with 1.32% above and 25.00% below the recommended range. Post-transplant duration was significantly associated with abnormal TAC C0 levels (OR = 1.167, p < 0.001). Conclusion: The majority of kidney transplant recipients, over one year post-transplant, achieved TAC C0 within the recommended range. Post-transplant duration was the only factor significantly associated with abnormal C0 levels. 

Keywords

Renal transplantation, Tacrolimus, Trough concentrations

Article Details

References

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