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Ngày xuất bản: 28/04/2023
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DOI: https://doi.org/10.56535/jmpm.v48i4.289
Số xuất bản
Tập 48 Số 4 (2023): TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ SỐ 4 - 2023
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Trích dẫn bài báo
Nguyen, T. V., & Nguyen, T. S. (2023). ANTIMICROBIAL RESISTANCE OF ANAEROBIC BACTERIA ISOLATED AT VIET DUC UNIVERSITY HOSPITAL. Tạp chí Y Dược học Quân sự, 48(4), 143-149. https://doi.org/10.56535/jmpm.v48i4.289

ANTIMICROBIAL RESISTANCE OF ANAEROBIC BACTERIA ISOLATED AT VIET DUC UNIVERSITY HOSPITAL

Nguyen Thi Van1, , Nguyen Thai Son2
1 Microbiology Department, Viet Duc University Hospital
2 Microbiology Department, Military Hospital 103, Vietnam Military Medical University

Nội dung chính của bài viết

Tóm tắt

Objectives: To evaluate the antibiotic susceptibility of anaerobic bacteria strains isolated from clinical specimens at Viet Duc University Hospital. Subjects and methods: A descriptive study and lab analysis on 167 anaerobic isolates isolated from clinical specimens. Results: The highest rate of resistance to the isolates was observed for metronidazole (84.43%), followed by clindamycin (49.7%) and antibiotics in the carbapenem group (2.99% - 8.98%), respectively. The lowest rate of resistance was shown for piperacillin/tazobactam (1.2%). However, the rate of resistance to antibiotics was variable in isolated strains. In more detail, amoxicillin/clavulanate varied from 0.00% - 10.53%, piperacillin/tazobactam (0.00% - 2.17%), metronidazole (78.95 % - 93.75%), carbapenems (0.00% - 12.50%), moxifloxacin (0.00% - 10.53%), and clindamycin (40.00% - 85.42%). The susceptibility to metronidazole was 80.43% in 46 Bacteroides isolates and 4.17% in 48 Prevotella isolates. Compared to other antibiotics, the resistance to metronidazole is significantly high, specifically for Prevotella, with the highest rate of 93.75%. Conclusion: The rate of resistance to antibiotics in pathogenic anaerobic bacterial isolates fluctuated with amoxicillin/clavulanate (0.00% - 10.53%), piperacillin/tazobactam (0.00% - 2.17%), carbapenems (0.00% - 12.50%), moxifloxacin (0.00% - 10.53%), and clindamycin (40.00% - 85.42%). The resistance varied in different strains. Prevotella and Micromonas were shown to be less resistant to antibiotics than Bacteroides and Clostridium.

Chi tiết bài viết

Từ khóa

Antimicrobial resistance, Anaerobic bacteria

Tài liệu tham khảo

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