ĐÁNH GIÁ TÁC DỤNG CHỐNG VIÊM, LONG ĐỜM CỦA BÀI THUỐC BỔ PHẾ ĐỊNH SUYỄN TRÊN MÔ HÌNH THỰC NGHIỆM

Trâm Anh Nguyễn1, Thị Phương Thảo Nguyễn1, Thanh Hà Tuấn Nguyễn1,
1 Bệnh viện Quân y 103, Học viện Quân y

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Abstract

          Objectives: To evaluate the anti-inflammatory effects on Wistar rats and expectorating effects on Swiss mice of the herbal prescription Bo phe dinh suyen. Methods: Anti-inflammatory effects were evaluated according to the Winter et al. method, 1968. Expectorating effects were evaluated according to Engler and Szelenyi (1984) method. Dosage in grams of dry herbs. Results At the experimental doses of 18.2g/kg/day and 36.4g/kg/day, BPDS exhibited acute anti-inflammatory effects in the carrageenin-induced Wistar rats paw edema model, reducing paw edema. At doses of 31.2g/kg/day and 62.4g/kg/day, BPDS demonstrated expectorant effects in Swiss albino mice injected intraperitoneally with phenol red, increasing phenol red concentration in tracheal lavage fluid. Conclusion: The herbal prescription Bo phe dinh suyen shows demonstrating both anti-inflammatory and expectorant effects in experimental models.

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