KHẢO SÁT TÌNH HÌNH NHIỄM HUMAN PAPILLOMAVIRUS VÀ SỰ PHÂN BỐ CÁC TYPE NGUY CƠ CAO Ở PHỤ NỮ ĐẾN KHÁM PHỤ KHOA TẠI BỆNH VIỆN A THÁI NGUYÊN

Abstract

STUDY ON HUMAN PAPILLOMA VIRUS (HPV) PREVALENCE AND DISTRIBUTION  HIGH-RISK HPV GENOTYPES IN WOMEN TO EXAMINATION IN THAI NGUYEN A HOSPITAL

Objectives: To determine hpv prevalence and distribution high-risk human papillomavirus virus genotypes on women to examination in Thai Nguyen A Hospital

Materials and methods: cross-sectional description on 914 women to examination in Thai Nguyen A Hospital from 03/2023 to 05/2024. All subjects have taken an pelvic examination to get clinical findings, samples taken from cervical will be extracted for DNA, apply realtime PCR technique to detect positive samples; this positive sample will be indentified for the HPV type by realtime PCR.

Results: The prevalence of HPV infection on patients at Thai Nguyen A Hospital was 18,82%, Age 26-35 years old have a higher rate than other groups (24,7%), mainly in rural areas.14 high-risk type include: 16, 18, 31, 33, 35, 39, 41, 45, 52, 53, 58, 59, 66 and 68, in which the rate of 12 other hrHPV accounted for the highest (62,79%). In most cases only one type of HPV infection (67,44%), two type of infection was 11,05% and 3 type infection accounted for 21,51%

Conclusion: The prevalence of genital HPV on women to examination in THAI NGUYEN A Hospital was , mainly in rural areas, most cases with high-risk HPV. There is similarity in HPV types distribution in Vietnam and in an other regions. The routine HPV screening should be carefully considered in prevention strategies and early detection of precancerous lesions of the cervix.

Key words: Human papillomavirus, HPV genotype