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Date Published: 06/10/2024
Abstract Views: 2
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DOI: https://doi.org/10.56535/jmpm.v49si1.939
Issue
Vol. 49 No. si1 (2024): TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ - SỐ ĐẶC BIỆT 10/2024
Section
Hội nghị Khoa học Ghép tạng toàn quốc lần thứ IX
How to Cite
Đinh, T. H., Phan, B. N., & Lê, V. T. (2024). SERUM TESTOSTERONE CONCENTRATION CHANGES IN MEN KIDNEY TRANSPLANT RECIPIENTS AT MILITARY HOSPITAL 103. Journal of Military Pharmaco-medicine, 49(si1), 113-122. https://doi.org/10.56535/jmpm.v49si1.939

SERUM TESTOSTERONE CONCENTRATION CHANGES IN MEN KIDNEY TRANSPLANT RECIPIENTS AT MILITARY HOSPITAL 103

Trọng Hà Đinh1, Bá Nghĩa Phan2, , Việt Thắng Lê2
1 Bộ môn Sinh lý học, Học viện Quân y
2 Bệnh viện Quân y 103, Học viện Quân y

Main Article Content

Abstract

Objectives: To assess changes in serum testosterone concentration in men kidney transplant recipients from living donors at Military Hospital 103. Methods: This was a prospective, longitudinal, descriptive study with analysis conducted on 45 men patients who successfully underwent kidney transplantation from March 2023 to May 2024. Results: The mean serum testosterone concentration in men kidney transplant recipients was 13.64 (11.4–15.99) nmol/L, a statistically significant improvement compared to pre-transplant (12.09 (10.09–15.0) nmol/L), p=0.04; 13.33% (6/45 patients) had reduced serum testosterone concentration, with 8.89% of new cases occurring post-transplant. The serum testosterone concentration had a significant positive correlation with IIEF-5 score (erectile function assessment), r=0.32, p=0.031. Logistic regression analysis indicated that the trough concentration C0 of Tacrolimus was an independent factor associated with the occurrence of reduced serum testosterone level in men kidney transplant recipients, OR=1.933 (CI95% 1.008 – 3.707). Conclusion: Serum testosterone concentration in men patients 6 months after kidney transplantation improved compared to pre-transplant but remained low, associated with erectile dysfunction and tacrolimus trough concentrations.

Article Details

Keywords

Kidney transplant, Testosterone, IIEF-5 score

References

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