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OUTCOMES OF LIVER TRANSPLANTATION FOR HEPATOCELLULAR CARCINOMA CAUSED BY CHRONIC HEPATITIS B IN VIET DUC UNIVERSITY HOSPITAL
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Abstract
Objectives: Evaluating the outcome of liver transplantation for hepatocellular carcinoma caused by hepatitis B at Viet Duc University hospital. Methods: The retrospective study of 48 patients with hepatocellular carcinoma (HCC) with hepatitis B performed liver transplantation at VietDuc University hospital from 5/2012 – 5/2022. Result: Average age 54.71 ± 8.41, pre-liver transplant adjuvant treatment with TACE or RFA accounted for 81.3%, 21.8% had pre - liver transplant alpha fetoprotein (AFP) > 200 ng/ml. Child-Pugh A 75%, within Milan criteria 39.6%. Living donor liver transplantation 18.8%, brain death donor liver transplantation 81.2%, cold ischemic time 167.6 ± 83.5 minutes. Hepatic thrombosis and portal vein thrombosis 4.2%, bleeding 4,2%, 90-day mortality 6.3%. The overall survival at 1 - year, 3 - year and 5 - year is 85.4%, 83.2 % và 83.2%. The disease - free survival at 1 – year, 3 – year and 5 – year 86.5%, 81.1% và 81.1%. Conclusion: Liver transplantation is an effective treatment for hepatocellular carcinoma due to hepatitis B.
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Keywords
liver transplantation, hepatocellular carcinoma, hepatitis B
References
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