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Date Published: 28/09/2024
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DOI: https://doi.org/10.56535/jmpm.v49i7.884
Issue
Vol. 49 No. 7 (2024): TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ SỐ 7 - 2024
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Articles
How to Cite
Nguyễn, H. N., Nguyễn, K. L., Ngô, V. Đ., Nguyễn, X. K., & Mai, H. T. (2024). PREDICTIVE VALUE OF METABOLIC PARAMETERS ON 18F-FDG PET/CT FOR REGIONAL LYMPH NODE METASTASIS IN SURGICALLY NON-SMALL CELL LUNG CANCER PATIENTS. Journal of Military Pharmaco-medicine, 49(7), 97-106. https://doi.org/10.56535/jmpm.v49i7.884

PREDICTIVE VALUE OF METABOLIC PARAMETERS ON 18F-FDG PET/CT FOR REGIONAL LYMPH NODE METASTASIS IN SURGICALLY NON-SMALL CELL LUNG CANCER PATIENTS

Hải Nguyễn Nguyễn1, , Nguyễn Kim Lưu1, Ngô Văn Đàn1, Nguyễn Xuân Khái1, Mai Huy Thông2
1 Trung tâm Chẩn đoán hình ảnh, Bệnh viện Quân y 103, Học viện Quân y
2 Khoa Y học hạt nhân, Bệnh viện Trung ương Quân đội 108

Main Article Content

Abstract

Objective: To investigate the derived parameters assessed on 18F-FDG PET/CT in predicting regional lymph node metastasis in surgically non-small cell lung cancer patients.


Subjects and Methods: A retrospective study was conducted on 55 NSCLC patients who underwent 18F-FDG PET/CT imaging before specific treatment at the Department of Nuclear Medicine, 103 Military Hospital, from December 2016 to January 2024, followed by lobectomy and regional lymph node dissection. Data were processed and analyzed using SPSS 26.0 software.


Results: Volume parameters, CoV b, CoV 41%, and I/C SUV ratio were significantly higher in the group with lymph node metastasis. The AUC area of ROC curve for CoV b, CoV 41%, MTV b, MTV 41%, TLG b were 0.830, 0.723, 0.705, 0.690, 0.676, respectively. Univariate analysis showed that CoV b, CoV 41%, MTV b, MTV 41%, TLG b, were prognostic factors for lymph node metastasis. Multivariate analysis identified CoV b, CoV41%, MTV b as independent prognostic factors for lymph node metastasis.


Conclusion: Tumor heterogeneity (CoV 41%, CoV b) and MTV b were independent prognostic factors for lymph node metastasis in surgically non-small cell lung cancer patients.





 


 


 

 


Article Details

Keywords

Heterogeneity, Volume parameters, Non-Small Cell Lung Cancer, PET/CT, Lymph Node Metastasis

References

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