ĐÁNH GIÁ TÁC DỤNG CỦA SẢN PHẨM DUNG DỊCH HỖ TRỢ CHĂM SÓC BỎNG TRÊN MÔ HÌNH BỎNG DA THỰC NGHIỆM

Abstract

Objective: Evaluating the skin burn treatment effect of the advanced burn care support solution (ABCSS) in vivo. Subjects and Methods: Research on rats causes skin burns with burn degrees I, II, III and treatment with ABCSS. For degree III burns, compare the effectiveness between 03 groups treated with ABCSS, SSD cream 1% and NaCl 0.9%. Collect clinical and paraclinical characteristics data on systemic and local injury site. Results: Treatment with ABCSS was safe, the rat's overall condition was stable, blood tests, liver and kidney tests were normal. The time to completely heal from degree I burns is 14 ± 1 day, for degree II burns is 22± 2 days, for degree III burns is 28 ± 1 day. For degree III skin burns, ABCSS has anti-inflammatory and antibacterial effects equivalent to SSD 1%. The appearance of burn lesions after healing in the ABCSS treatment group is more beautiful, leaving no scars, and histopathological testing is more accurate. The rate of complete skin healing is higher (75%).Conclusion: In vivo, ABCSS is effective in treating skin burns of all levels, stimulating quick wound healing, and effectively sterilizing common bacterial strains in burn wounds.