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Date Published: 28/09/2024
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DOI: https://doi.org/10.56535/jmpm.v49i7.862
Issue
Vol. 49 No. 7 (2024): TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ SỐ 7 - 2024
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Articles
How to Cite
Hà, V. Q., & Trần, T. T. (2024). STUDY ON THE PROGNOSTIC VALUES OF PROGNOSTIC NUTRITIONAL INDEX IN PATIENTS WITH MULTIPLE MYELOMA. Journal of Military Pharmaco-medicine, 49(7), 163-172. https://doi.org/10.56535/jmpm.v49i7.862

STUDY ON THE PROGNOSTIC VALUES OF PROGNOSTIC NUTRITIONAL INDEX IN PATIENTS WITH MULTIPLE MYELOMA

Văn Quang Hà1, , Thị Tâm Trần1
1 Bộ môn - Trung tâm Nội Dã chiến, Bệnh viện Quân y 103, Học viện Quân y

Main Article Content

Abstract

Objective: To conduct a study on the prognostic values of the Prognostic Nutritional Index (PNI) for patients with multiple myeloma receiving treatment at Military Hospital 103 between 2014 and 2023. Subjects and methods: 64 patients were diagnosed and treated for multiple myeloma at Military Hospital 103 from January 2014 to December 2023. Results: For patients with multiple myeloma, the PNI index has a cutoff value of 43.1 for overall survival (OS). The risk progression of multiple myeloma was reduced by 53% and the risk of death of multiple myeloma was reduced by 62% in patients with a PNI > 43.1 compared with patients with a PNI ≤ 43.1. The PNI > 43.1 group had progression-free survival (PFS) of 34.0 ± 6.7 (months), which was significantly higher than the PNI ≤ 43.1 group (PFS = 16.6 ± 3.8 (months)), with p = 0.018. The overall survival (OS) of the PNI > 43.1 group was 63.0 ± 12.4 (months) which was statistically significantly longer than the PNI ≤ 43.1 group (OS = 24.4 ± 3,7 (months)), with p = 0.008. Conclusion: PNI is a highly valuable index in the prognosis of patients with multiple myeloma.

Article Details

Keywords

Multiple myeloma, Prognostic Nutritional Index, Military Hospital 103

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