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Date Published: 28/10/2024
Abstract Views: 4
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DOI: https://doi.org/10.56535/jmpm.v49i8.851
Issue
Vol. 49 No. 8 (2024): TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ SỐ 8 - 2024
Section
Articles
How to Cite
Trương, Đ. T., Trần, N. D., Phạm, M. N., & Hoàng, M. T. (2024). ĐÁNH GIÁ TỶ LỆ XÂM NHIỄM LYMPHO TRONG MÔ ĐỆM VÙNG RÌA MÔ UNG THƯ BIỂU MÔ ĐẠI TRỰC TRÀNG. Journal of Military Pharmaco-medicine, 49(8), 56-65. https://doi.org/10.56535/jmpm.v49i8.851

ĐÁNH GIÁ TỶ LỆ XÂM NHIỄM LYMPHO TRONG MÔ ĐỆM VÙNG RÌA MÔ UNG THƯ BIỂU MÔ ĐẠI TRỰC TRÀNG

Đình Tiến Trương1, , Ngọc Dũng Trần1, Minh Nghĩa Phạm2, Mỹ Tâm Hoàng2
1 Bộ môn - Khoa Giải phẫu bệnh lý, Pháp y, Bệnh viện Quân y 103
2 Hệ 2, Học viện Quân y

Main Article Content

Abstract

Objectives: To investigate the tumor-infiltrating lymphocytes in invasive margins and the correlation with pathologic features in patients with colorectal cancer. Methods: A cross-sectional descriptive study was conducted on 131 patients diagnosed with colorectal cancer and surgically resected at Military Hospital 103. The tumor samples were processed according to standardized pathological procedures. TILs in the invasive margin were assessed on tumor slides, and their correlation with pathologic features was evaluated. Results: The mean percentage of TILs was 14.96% with a standard deviation of 17.5% and a median of 5%, the higher percentage of TILs was significantly associated with good prognosis pathological factors including tumors with lower tumor stages, low grades, early TNM stages, and non-perineural invasion. Conclusion: The tumor-infiltrating lymphocytes could play a significant prognostic role in patients with colorectal carcinoma.

Article Details

Keywords

tumor-infiltrating lymphocytes, colorectal carcinoma

References

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