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THE MORTALITY PROGNOSTIC VALUE OF NEUTROPHIL TO LYMPHOCYTE RATIO AND GLASGOW COMA SCALE AT ADMISSION TIME IN TRAUMATIC BRAIN INJURY PATIENTS
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Abstract
Objective: To assess the mortality prognostic value of the Neutrophil/ Lymphocyte ratio (NLR) in traumatic brain injury (TBI) patients. Method: A prospective, cohort study on 65 traumatic brain injury, over 16 years old, treated at Surgical Intensive Care Unit - Military Hospital 103 from January 2021 to March 2024. Consiousness level and severity was assessed based on Glasgow coma scale (GCS), and clinical, sub-clinical factor was calculated at admission prior to any treatment intervention. Datas according to research medical records, datas were coded and processed according to statistical methods. Results: The majority of TBI patients were male (78.5%), patients are mainly of working age (16 - 59) account for 72.3%, with the main cause being traffic accidents (72.3%). The NLR value at admission demonstrated predictive value for mortality in traumatic brain injrury patients with an AUC of 0.76, a cut-off of 13.26, sensitivity Se = 0.533 and specificity Sp = 0.914 were achieved. The prognostic model combining GCS and NLR has better mortality prognostic value than NLR alone with an AUC of 0.86; sensitivity Se = 0.773 and specificity Sp = 0.886. Conclusion: The NLR value at the time of admission and the prognostic model combining GCS – NLR had a significant prognostic value for mortality in traumatic brain injury patients
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Keywords
Traumatic Brain Injury, Mortality Prognostic, Neutrophil to Lymphocyte Ratio
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