SOME FEATURES OF ADULT PATIENTS WITH CHRONIC FUNGAL RHINOSINUSITIS IN 103 MILITARY HOSPITAL

Quan Thanh Nam , Nghiêm Đức Thuận, Nguyen Phi Long, Đình Hồng Phúc Nguyễn1, Hong Thu Tran
1 Bệnh viện Quân y 103, Học viện Quân y

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Abstract

Objective: To describe some clinical, subclinical features of chronic fungal rhinosinusitis in adult patients. Materials and methods: A prospective, case-by-case study was conducted on 41 patients diagnosed with chronic fungal rhinosinusitis at Military Hospital 103 from October 2022 to April 2023. Results: The average age was 60.34 ± 13.78 years; genders were similar. The most prevalent functional symptoms were nasal congestion (82.9%) and nasal discharge (80.5%); pus oozing from the middle meatus accounted for 82.9%. Computed tomography (CT) scans revealed maxillary sinus opacification predominantly on one side (78%); increased density (calcification) was observed between the homogeneous opacities in the sinus in 95.1% of cases. The positivity rate on direct microscopy was 22%, and on fungal cultures, it was 27%. Aspergillus species were identified in all cases. Pathological findings indicated fungal hyphae in 95.1% of cases, with no evidence of fungal invasion into the tissues. Conclusion: Chronic fungal rhinosinusitis exhibits common symptoms observed in chronic rhinosinusitis patients. Endoscopy revealed pus primarily emanating from the middle meatus, and CT scans commonly showed increased density images. The most common type of fungus was Aspergillus, and histopathology showed no invasion of the sinus mucosa.

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References

1. Wormald PJ, Alkis PT, Bassiouni A, et al. Role of fungi in chronic rhinosinusitis through ITS sequencing. The Laryngoscope. 2018; 128(1):16-22.
2. Fadda GL, Succo G, Moretto P, et al. Endoscopic endonasal surgery for sinus fungus balls: Clinical, radiological, histopathological, and microbiological analysis of 40 cases and review of the literature. Iranian Journal of Otorhinolaryngology. 2019; 102(1):35-44.
3. Schubert MS. Fungal rhinosinusitis: Diagnosis and therapy. Current Allergy and Asthma Reports. 2001; 1(3):268-276.
4. Hà Phương Thảo. Nghiên cứu đặc điểm lâm sàng, cận lâm sang và kết quả phẫu thuật nội soi mũi xoang điều trị viêm xoang do nấm. Tạp chí Y học Việt Nam. 2023; 1:126-128.
5. Kaur R, Lavanya S, Khurana N, et al. Allergic fungal rhinosinusitis: A study in a tertiary care hospital in India. Journal of Allergy. 2016:1-6.
6. Huỳnh Vĩ Sơn. Góp phần chẩn đoán và điều trị viêm mũi xoang do nấm tại Trung tâm Tai mũi họng Thành phố Hồ Chí Minh. Luận văn Chuyên khoa cấp 2, Đại học Y dược Thành Phố Hồ Chí Minh. 2001.
7. Vũ Thị Ly. Đặc điểm lâm sàng và đánh giá kết quả phẫu thuật nội soi mũi xoang kết hợp rửa mũi sau mổ bằng máy nhịp xung điều trị viêm mũi xoang do nấm không xâm lấn. Tạp chí Y học Việt Nam. 2023; 2:54-58.
8. Nicolai P, Lombardi D, Tomenzoli D, et al. Fungus ball of the paranasal sinuses: Experience in 160 patients treated with endoscopic surgery. The Laryngoscope. 2009; 119(11):2275-2279.
9. Klossek JM, Serrano E, Péloquin L, et al. Functional endoscopicsinus surgery and 109 mycetomas of paranasal sinuses. The Laryngoscope. 1997; 107(1):112-117
10. Nguyễn Ngọc Minh. Nghiên cứu nhiễm nấm trong viêm mũi xoang mạn tính có polyp mũi. Y học thành phố Hồ Chí Minh. 2014; 18(1):25-31.