GIÁ TRỊ CỦA SINH THIẾT THẬN DƯỚI HƯỚNG DẪN CỦA CHỤP CẮT LỚP VI TÍNH TRONG CHẨN ĐOÁN U THẬN

Abstract

Objectives:  CT-guided kidney biopsy is the gold standard for obtaining renal tissue samples. This study aimed to describe the diagnostic yield and complications of CT-guided kidney biopsies in patients with solid renal masses.

Materials and methods:  We performed a cross-sectional, single-center. Biopsy performance was compared with surgical pathology results. Complications were defined as hematoma, pneumothorax, ascites, nephrectomy.

Results: 27 CT-guided native kidney biopsies were performed during the study period, there were 22 tumors whose histopathology was kidney cancer, of which clear cell carcinoma was the most common, accounting for 45.45%. The results of percutaneous needle biopsy under CT guidance for diagnosing malignant kidney tumors show a sensitivity of 94.40%, specificity of 100%, positive predictive value of 66.67%, negative predictive value of 100%, and accuracy of 95%. The agreement of histopathological results between the biopsy and surgery is very good, with Cohen's Kappa coefficient = 0.773. Complications have a rate of 37.04%, all cases are asymptomatic hematomas, with no other complications. Closely monitoring clinical signs shows that most complications are stable and do not require treatment.

Conclusions: Percutaneous renal mass biopsy under CT guidance can be performed safely and effectively, with a low complication rate and a high diagnostic yield.