BRAINSTEM GLIOMA: PREDICTION OF HISTOPATHOLOGIC GRADE BASED ON CONVENTIONAL MR IMAGING
Main Article Content
Abstract
Objectives: A retrospective study was designed to investigate the value features on MR imaging in differentiating low-grade and high-grade brainstem gliomas. Methods: Retrospective study was performed in 36 patients including 20 children and 16 adults, with pathological results of brainstem glioma. Analysis features of brainstem glioma on conventional MRI to determine the sensitivity, specificity of signs to help distinguish low-grade and high-grade. Results: In children, tumors located in the midbrain, in the tectorial membrane, invading the fourth ventricle, localized, and having cystic components have the value of suggesting low-grade brainstem glioma with sensitivity and specificity of each sign are 83.3% and 71.4%, 50% and 100%, 50% and 92.9%, 33.3% and 100%, 50% and 92.9%, respectively. Tumors have diffusetively and hemorrage components suggest high-grade brainstem glioma with sensitivity and specificity of each sign being 100% and 33.3%, 64.3% and 100%, respectively. In adults, hemorrage components have a suggestive value of high-grade brainstem glioma with sensitivity and specificity of 50% and 100%. Conclusion: In children, location in the midbrain/tectum, focal lesions, invasion of the fourth ventricle, cystic component suggest low-grade brainstem glioma, diffuse and hemorrage suggest high-grade brainstem glioma. In adults, hemorrage characteristics suggest high-grade brainstem glioma.
Article Details
Keywords
MRI, brainstem glioma, grading glioma
References
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