INITIAL EVALUATION OF THE RESULTS OF PROSTATIC ARTERY EMBOLIZATION USING N-BUTYL CYANOACRYLATE

Phan Hoang Giang , Hồng Đức Trương, Huy Hoàng Nguyễn, Thị Hương Nguyễn, Thị Thúy Hằng Trần, Minh Tuấn Nguyễn, Đào Vũ Đỗ, Đăng Lưu Vũ

Main Article Content

Abstract

Objective: evaluate the clinical effectiveness and safety of endovascular prostate intervention using glue in the treatment of benign prostatic hypertrophy


Methods: We performed embolization prostatic artery in 16 patients (mean age, 73.6 years; age range 65-85) at the Radiology Center, Bach Mai Hospital from June 2022 to January 2023.


Results: Rate Technical success rate is 100%, clinical success rate and 100% technical success rate. No major complications occurred. There was a significant improvement in IPSS, QoL, Qmax before and after 6 months of intervention.


Conclusion: glue is a safe material that can be widely used in the future as a replacement material for polyvinyl microplastics, contributing to reducing irradiation time and reducing costs for patients, but doctors need to know usage experienc

Article Details

References

1. Cormio L, Calò B, Falagario U, et al. Improvement of urinary tract symptoms and quality of life in benign prostate hyperplasia patients associated with consumption of a newly developed whole tomato-based food supplement: A phase II prospective, randomized double-blinded, placebo-controlled study. J Transl Med. 2021; 19(1):24. DOI:10.1186/s12967-020-02684-3.
2. Carnevale FC, Iscaife A, Yoshinaga EM, Moreira AM, Antunes AA, Srougi M. Transurethral Resection of the Prostate (TURP) Versus Original and PErFecTED Prostate Artery Embolization (PAE) Due to Benign Prostatic Hyperplasia (BPH): Preliminary results of a single center, prospective, urodynamic-controlled analysis. Cardiovasc Intervent Radiol. 2016; 39(1):44-52. DOI:10.1007/s00270-015-1202-4.
3. Geevarghese R, Harding J, Parsons N, Hutchinson C, Parsons C. The relationship of embolic particle size to patient outcomes in prostate artery embolisation for benign prostatic hyperplasia: A systematic review and meta-regression. Clin Radiol. 2020; 75(5):366-374. DOI:10.1016/j.crad. 2019.12.019.
4. Abdulmalak G, Chevallier O, Falvo N, et al. Safety and efficacy of transcatheter embolization with Glubran®2 cyanoacrylate glue for acute arterial bleeding: A single-center experience with 104 patients. Abdom Radiol (NY). 2018; 43(3):723-733. DOI:10.1007/s00261-017-1267-4.
5. Loffroy R, Guiu B, Cercueil JP, Krausé D. Endovascular therapeutic embolisation: An overview of occluding agents and their effects on embolised tissues. Curr Vasc Pharmacol. 2009; 7(2): 250-263. DOI:10.2174/157016109787455617.
6. Ray AF, Powell J, Speakman MJ, et al. Efficacy and safety of prostate artery embolization for benign prostatic hyperplasia: An observational study and propensity-matched comparison with transurethral resection of the prostate (the UK-ROPE study). BJU Int. 2018; 122(2):270-282. DOI:10.1111/ bju.14249.
7. Loffroy R, Guillen K, Salet E, et al. Prostate artery embolization using n-butyl cyanoacrylate glue for urinary tract symptoms due to benign prostatic hyperplasia: A valid alternative to microparticles? JCM. 2021;10(14):3161. DOI:10.3390/jcm10143161.
8. Carnevale FC, Moreira AM, de Assis AM, et al. Prostatic artery embolization for the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia: 10 Years’ experience. Radiology. 2020; 296(2): 444-451. DOI:10.1148/radiol.2020191249.
9. Kuang M, Vu A, Athreya S. A systematic review of prostatic artery embolization in the treatment of symptomatic benign prostatic hyperplasia. Cardiovasc Intervent Radiol. 2017; 40(5):655-663. DOI:10.1007/s00270-016-1539-3.
10. Li YJ, Barthès-Biesel D, Salsac AV. Polymerization kinetics of a mixture of Lipiodol and Glubran 2 cyanoacrylate glue upon contact with a proteinaceous solution. J Mech Behav Biomed Mater. 2017; 74:84-92. DOI:10.1016/j.jmbbm.2017.05.023.