CĂN NGUYÊN VÀ TÌNH TRẠNG KHÁNG KHÁNG SINH CỦA MỘT SỐ VI KHUẨN GÂY BỆNH THƯỜNG GẶP TẠI TRUNG TÂM HỒI SỨC CẤP CỨU - CHỐNG ĐỘC, BỆNH VIỆN QUÂN Y 103

Abstract

Research on the etiology and antimicrobial resistance at the Intensive care unit in the Military Hospital 103

ABSTRACT

Objective: To investigate the etiology and antimicrobial resistance of some common pathogenic bacteria at the Intensive care unit (ICU) - Military Hospital 103. Subject: Bacterial strains isolated through specimens of patients in ICU - 103 Military Hospital from January 2020 to December 2021. Research methods: Descriptive epidemiology and laboratory study. Results: 282 strains of pathogenic bacteria were isolated; including 56.4% from the respiratory tract specimens (56.4%); of which bronchial fluid and sputum were 44.3% and 12.1%, respectively; blood specimens were 29.4%. Gram-negative bacteria accounted for the vast majority of 87.6%; Gram-positive bacteria were only just 12.4%. Among gram-negative organisms, A. baumannii and P. aeruginosa were the most common species, each of them accounted for 29.4%; K. pneumonia and E. coli were 9.6% and 9.2%, respectively. In gram-positive bacteria; S. aureus accounted for the highest rate of 3.9%; S. pneumonia was 1.4%; E. faecalis was 1.1%. A. baumannii and P. aeruginosa were resistant to the vast majority of commonly used antibiotics. A. baumannii A. baumannii was resistant to Meropenem 96.3%, Imipenem 100%; Colistin 62.8%; Amikacin 89.1%. P. aeruginosa was resistant to Imipenem 87.5%; Meropenem 77.5%; Amikacin 62.4%; Colistin 47.4%. S. aureus was resistant to Cefoxitin 75%, resistant to commonly used antibiotics ranging from 50 to 70% (Ceftriaxone 62.5%; Meropenem 70.0%; Moxifloxacin 50.0%); were highly susceptible to agents used for MRSA strains such as Vancomycin 85.7%; Linezolid and Tigercylin were both 100.0%. Conclusion: The bacteria strains isolated from patients in ICU were most common Gram-negative bacteria, by respiratory specimens, showed high rates of antibiotic resistance.