GIÁ TRỊ TIÊN LƯỢNG TỬ VONG CỦA TỶ LỆ LACTATE/ALBUMIN THỜI ĐIỂM VÀO VIỆN Ở BỆNH NHÂN CHẤN THƯƠNG SỌ NÃO NẶNG

Abstract

Objectives: To determine the mortality prognostic value of the Lactate/Albumin ratio in severe traumatic brain injury (TBI) patients. Study design: descriptive, prospective study on severe TBI patients who admitted to the surgery intensive care unit of Military Hospital 103. Patients' clinical and subclinical data were collected at the time of admission and discharge. The data are encoded and processed according to statistical methods. Results: The majority of severe TBI patients are aged 20-40 (30.6%), mainly men (77.4%), and the main cause is traffic accident (72.6%). The death group had a statistically significant higher Lactate/Albumin ratio than the survival group (p<0.05). Lactate/Albumin ratio was strongly correlated with Lactate at admission (r = 0.905; p < 0.001), moderately correlated with Rotterdam score (r = 0.427; p = 0.009) and Glasgow score (r = -0.381; p = 0.011). The area under the mortality prediction curve of Lactate/Albumin ratio was higher than lactate alone (0.735 and 0.708, respectively). Multivariable logistic regression model based on age, Glasgow score at admission and Lactate/Albumin ratio had a higher mortality prognostic significance than the lactate/albumin ratio alone with an area under the curve of 0.840. Conclusions: Lactate/Albumin ratio is meaningful in predicting mortality with an area under the curve of 0.735; higher than that of lactate alone (0.708). Multivariable logistic regression model based on age, Glasgow score at admission and Lactate/Albumin ratio had a higher mortality prognostic significance than the Lactate/Albumin ratio alone with an area under the curve of 0.840.