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Date Published: 20/12/2023
Abstract Views: 43
Views PDF: 71
DOI: https://doi.org/10.56535/jmpm.v48i9.530
Issue
Vol. 48 No. 9 (2023): TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ SỐ 9 - 2023
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Articles
How to Cite
Võ, V. H. (2023). EFFECTIVENESS OF PHENYLEPHRINE IN PREVENTING HYPOTENSION POST-INDUCTION ANESTHESIA WITH PROPOFOL IN PATIENTS UNDERGOING BURN NECROSECTOMY AND SKIN GRAFTING SURGERY. Journal of Military Pharmaco-medicine, 48(9), 86-94. https://doi.org/10.56535/jmpm.v48i9.530

EFFECTIVENESS OF PHENYLEPHRINE IN PREVENTING HYPOTENSION POST-INDUCTION ANESTHESIA WITH PROPOFOL IN PATIENTS UNDERGOING BURN NECROSECTOMY AND SKIN GRAFTING SURGERY

Văn Hiển Võ

Main Article Content

Abstract

Objectives: To evaluate the effectiveness of phenylephrine in preventing hypotension when combined with propofol for induction of anesthesia in burn necrosectomy and skin grafting surgery. Methods: An intervention clinical study was conducted on 100 patients, aged 18 - 60, ASA I-II, with no medical history of cardiovascular disease, who were randomly divided into 2 groups: Group 1 (n = 50) was anesthetized with propofol combined with phenylephrine at a dose of 50mcg; group 2 (n = 50) was anesthetized with propofol combined with phenylephrine at a dose of 100mcg. Results: Patients in group 1 had lower systolic, diastolic, and mean blood pressure from the first to the fifth minutes following the induction of anesthesia (p < 0.05); group 1 had a hypotension rate of 48%, higher than that of group 2 (20%), with p < 0.05. Conclusion: Phenylephrine at doses of 100mcg combined with propofol has a good effect in preventing hypotension during the induction of anesthesia in patients undergoing burn necrosectomy and skin grafting surgery.

Article Details

Keywords

Hypotension, Induction anesthesia, Propofol, Phenylephrine

References

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