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RELATIONSHIP OF LEFT ATRIAL LONGITUDINAL STRAIN AND LEFT ATRIOVENTRICULAR COUPLING WITH LEFT VENTRICULAR DIASTOLIC DYSFUNCTION AND NT-PROBNP LEVELS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION UNDERGOING PERCUTANEOUS CORONARY INTERVENTION
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Abstract
Objectives: To investigate left atrial strain and left atrioventricular coupling by echocardiography in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI). Methods: A cross-sectional descriptive, retrospective and prospective study on 66 patients with AMI treated with PCI. The patients had blood tests, and echocardiography measured the parameters of left atrial strain and left atrioventricular coupling at two timepoints: within 24 hours after admission and 7 days after PCI. Results: Left atrial reserve strain (LASr) was inversely correlated with E/E' septal (r = -0.28, p = 0.027), E/E' lateral (r = -0.29, p = 0.022), LAVmax (r = -0.42, p = 0.024), and NT-proBNP levels (r = -0.44, p = 0.001). The left atrioventricular coupling index (LACI) was positively correlated with E/E' lateral (r = 0.43, p = 0.021), LAVmax (r = 0.77, p < 0.001), and inversely correlated with LAEF (r = -0.57, p = 0.001), LASr (r = -0.38, p = 0.037). Conclusion: LASr and LACI were positively correlated with left ventricular diastolic dysfunction, LASr was negatively correlated with NT-proBNP levels, and LACI was inversely correlated with LASr in patients with AMI.
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Keywords
Acute myocardial infarction, Left atrial strain, Left atrioventricular coupling, Left ventricular diastolic dysfunction, NT-proBNP
References
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