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Date Published: 28/06/2023
Abstract Views: 266
Views PDF: 404
DOI: https://doi.org/10.56535/jmpm.v48i5.369
Issue
Vol. 48 No. 5 (2023): JOURNAL OF MILITARY PHARMACO-MEDICINE 5-2023
Section
Articles
How to Cite
Đỗ, X. H. (2023). RESEARCH ON THE PRODUCTION OF HUMAN UMBILICAL CORD PLATELET-RICH PLASMA GEL. Journal of Military Pharmaco-medicine, 48(5), 37-43. https://doi.org/10.56535/jmpm.v48i5.369

RESEARCH ON THE PRODUCTION OF HUMAN UMBILICAL CORD PLATELET-RICH PLASMA GEL

Xuan Hai Đỗ1,
1 Học viện Quân y

Main Article Content

Abstract

Objectives: This study aimed to prepare platelet-rich plasma (PRP) gel from human umbilical cord artery blood. Methods: PRP were obtained from umbilical cord artery blood and activated by CaCl2 (10%)/Thrombin 2/5 (mL) solution in the appropriate ratio. Platelet ratio and purity of good quality according to DEPA classification of Magalon J. Results: The obtained PRP had an average platelet count of 6.5 ± 1.5 × 109 platelets/mL, eight times higher than whole blood. According to the DEPA classification, platelet recovery rate and purity reached a high-quality level. The activation process is of near-ideal quality. The optimal PRP/CaCl2 (10%)/Thrombin ratio is 1/2/5. Conclusion: Successfully prepared PRP gel from cord blood with platelet concentration 8 times higher than whole blood, light yellow color and purity from 3.9+.

Article Details

Keywords

Platelet-rich plasma (PRP), Umbilical cord blood, Platelet activation

References

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