ANXIETY AND DEPRESSION DISORDERS ASSESSED BY THE HADS IN PATIENTS WITH IRRITABLE BOWEL SYNDROME

Trung Nam Phan , Quốc Khánh Trần

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Abstract

Background: Anxiety disorders (AD) and depression disorders (DD) are quite common in patients with irritable bowel syndrome (IBS). Objectives: To investigate the status of anxiety and depression using the HADS and some related factors in IBS patients. Subjects and methods: A cross-sectional descriptive study on 287 outpatients at Hue University of Medicine and Pharmacy Hospital were diagnosed with IBS and evaluated for AD and DD using the HADS through a questionnaire. Patients with red-flag symptoms were excluded through clinical examination. Results: The mean age of patients was 50.9, and females accounted for 51.0%. The types of IBS-C were at 25.4%, IBS-D at 13.6%, IBS-M at 25.8%, and IBS-U at 35.2%. According to the HADS, the proportion of patients with AD was 43.6%, and DD was 30.3%. Females were more likely to have AD and DD than males, with ORs of 1.66 and 1.96, respectively (p < 0.05). AD was more likely to occur in IBS patients with IBS-C (OR = 4.37), IBS-D (OR = 4.44), and IBS-M (OR = 5.59) when compared to IBS-U patients (p < 0.05). DD was more likely to occur in IBS patients with IBS-C (OR = 4.26), IBS-D (OR = 7.01), and IBS-M (OR = 6.59) than in IBS-U patients (p < 0.05). Conclusion: AD and DD are quite common in IBS patients, and these disorders are related to the types of IBS and gender. Therefore, it is necessary to evaluate AD and DD in IBS patients for diagnosis and management to achieve optimal results.

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References

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