KHẢO SÁT ĐẶC ĐIỂM THIẾU MÁU Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÝP 2 CÓ TỔN THƯƠNG THẬN

Abstract

Objectives: To investigate some features of anemia in type 2 diabetic mellitus (T2DM) patients with kidney injury. Subjects and methods: A cross-sectional study on 180 patients, including 129 patients diagnosed the type 2 diabetic mellitus with kidney injury and 51 T2DM patients without kidney injury. A complete blood count was done in all  patients to determine the prevalence and features of anemia. Results: The average Hb concentration was 115.79 ± 22.45g/L; the anemia rate was 65.1%. Among patients with anemia, mild and moderate anemia accounted for the majority, and only 7.1% had severe anemia. Anemia of average size and isochronic accounted for the majority, the rate was 88.1%. The rate of anemia in the group of CKD patients, CKD stage 5 was higher than those with MAU (+); MAC (+) or CKD stage 3+4, as well as CKD stage 1+2, p < 0.001. At a concentration of 37.1 g/L, serum albumin had a predictive value of anemia with an area under the curve of 0.787 (p < 0.001), and at the cut-off point of 37.3 mL/min, GFR also had a good predictive value with the area under the curve of 0.786, p < 0.001. Conclusion: Anemia is common in type 2 diabetic mellitus patients with kidney damage. Serum albumin concentration and glomerular filtration rate are two factors with good predictive value of anemia.