NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, KẾT QUẢ ĐIỀU TRỊ BỆNH NHÂN SỐC NHIỄM KHUẨN TẠI TRUNG TÂM HỒI SỨC CẤP CỨU - CHỐNG ĐỘC, BỆNH VIỆN QUÂN Y 103 NĂM 2022

Abstract

Objectives: To evaluate clinical characteristics and treatment outcomes in patients with septic shock in Intensive Care, Emergency and Poison Control Centre - Military Hospital 103 in 2022. Subjects and methods: A prospective descriptive study on 50 patients with septic shock over 18 years old from January to November 2022. Results: 50 patients were diagnosed with septic shock, of which 36 (72%) blood cultures were positive and 14/50 (28%) blood cultures were negative. A. baumannii and E. coli  were the most common agents (28% and 17%) in patients with septic shock. Age, gender, and GCS scores were similar between the two groups (p > 0.05). There was no significant difference between the two groups of negative and positive blood cultures in the proportion of patients requiring mechanical ventilation (57.14% vs. 61.1%; p > 0.05), the rate requiring renal replacement therapy. CRRT (57.14% vs. 44.4%; p > 0.05) and PCT concentration (49.9 ± 36.3 vs. 47.43 ± 40.5; p > 0.05). However, the mortality rate in the positive blood culture group was significantly higher (66.67% vs. 28.57%; p < 0.05). Age, sex, mean blood pressure, and blood lactate levels are risk factors associated with the incidence of bacterial culture-positive blood cultures. Conclusion: The mortality rate in septic shock patients with positive blood cultures was significantly higher than in negative blood cultures. Age, sex, mean blood pressure, and lactate concentration are independent risk factors related to the positive culture rate in septic shock patients.