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Issue: Vol. 51 No. 10 (2026): JOURNAL OF MILITARY PHARMACO-MEDICINE No.10 - 2026
Section: Articles
DOI: 10.56535/jmpm.v51i10.2334
Date Published: 28/10/2026
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How to Cite
Do, T. T., Nguyen, T. H., Nguyen, T. N., Hoang, V. D., Truong, T. T. H., Pham, H. Y., & Phan, V. K. (2026). CHEMICAL COMPOSITION AND NITRIC OXIDE INHIBITORY ACTIVITY OF MARANTA ARUNDINACEA LEAVES. Journal of Military Pharmaco-medicine, 51(10), 7-16. https://doi.org/10.56535/jmpm.v51i10.2334

CHEMICAL COMPOSITION AND NITRIC OXIDE INHIBITORY ACTIVITY OF MARANTA ARUNDINACEA LEAVES

Thi Trang Do1,2, Thi Ha Nguyen3,4, Thi Nga Nguyen2, Viet Dung Hoang5, Thi Thu Hien Truong5, Hai Yen Pham1, Văn Kiệm Phan1,
1 Vietnam Academy of Science and Technology, VAST
2 Hanoi Medical College
3 Vietnam Academy of Science and Technology
4 Ha Tinh Drug, Cosmetic and Food Testing Center
5 Vietnam Military Medical University

Main Article Content

Abstract

Objectives: To isolate compounds from Maranta arundinacea leaves and evaluate their inhibitory activity against NO production. Methods:This was an in vitro experimental study design. Compounds were isolated using chromatography; their structures were elucidated via NMR spectroscopy. Inhibitory activity against NO production was assessed using RAW 264.7 cells. Results: Seven compounds (1 - 7) were isolated. Compounds 5 and 6 demonstrated significant inhibition of NO production, with IC50 values ​​of 25.1µM and 37.5µM, respectively.Conclusion: Seven compounds belonging to the megastigman, flavonoid, and lignan classes were isolated from M. arundinacea leaves for the first time. Compounds 5 and 6 exhibited the strongest inhibitory activity against NO production.

Keywords

Maranta arundinacea, Marantaceae, Megastigman, Flavonoid, Lignan

Article Details

References

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