STUDY ON THE EFFECT OF HOAN LUC KHANG SOFT CAPSULES ON PHYSICAL RECOVERY AFTER COLD STRESS EXPERIMENT
Main Article Content
Abstract
Objectives: To evaluate the effect of Hoan luc khang (HLK) soft capsules on restoring physical strength after cold stress in experimental settings. Methods: This was an in vivo experimental study design. Core temperature, respiratory rate, red blood cell (RBC) count, activity level, and feeding behavior were assessed in rabbits subjected to forced exercise in a microclimate chamber at 15°C and 50% humidity. Results: HLK soft capsules helped restore core temperature to baseline faster, supported the maintenance of stable SpO₂, prevented respiratory depression, and increased activity and food intake compared to the herbal extracts and placebo groups. Conclusion: HLK soft capsules improved endurance and physical recovery under cold stress compared to herbal extracts and placebo groups.
Keywords
Hoan luc khang soft capsule, Cold stress, Physical recovery
Article Details
References
2. Nguyễn Ngô Quang. Hướng dẫn thử nghiệm tiền lâm sàng và lâm sàng thuốc đông y, thuốc từ dược liệu ban hành kèm theo Quyết định số 141/QĐ-K2ĐT ngày 27/10/2015. 2015.
3. Young AJ, Castellani JW. Exertion-induced fatigue and thermoregulation in the cold. Comparative Biochemistry and Physiology A. 2001;128:769-6.
4. Cannon B & Nedergaard J. Brown adipose tissue: function and physiological significance. Physiological Reviews. 2024;84(1):277-9.
5. Zhou L, et al. Acteoside from Cistanche deserticola stimulates brown adipose tissue activation and thermogenesis in high-fat-diet-induced obese mice. Journal of Agricultural and Food Chemistry. 2019;67(48):13253-2.
6. Tipton MJ, et al. Human physiological responses to cold exposure. Experimental Physiology. 2017;102(1):1-35.
7. Zhao J, et al. Phenylethanoid glycosides from Cistanche deserticola ameliorate hypothalamic-pituitary-adrenal axis dysfunction in chronically stressed mice. Frontiers in Pharmacology. 2018;9:45.
8. Castellani JW & Young AJ. Human physiological responses to cold exposure: acute responses and acclimatization to repeated exposure. Autonomic Neuroscience. 2016;196:63-74.
9. Chen J & Wang J. Advanced therapy of traditional chinese medicine for Qi and Yin Deficiency Syndrome. Journal of Traditional Chinese Medicine. 2010;30(3):235-8.