RELATIONSHIP BETWEEN LYMPH NODE METASTASIS AND TUMOR CHARACTERISTICS IN PATIENTS WITH NON-SMALL CELL LUNG CANCER POST THORACOSCOPIC LOBECTOMY AND LYMPH NODE DISSECTION
Main Article Content
Abstract
Objectives: To find out the lymph node metastasis depended on tumor characteristics in non-small cell lung cancer patients post thoracoscopic lobectomy and lymph node dissection. Subjects and methods: A prospective and descriptive study on lymph node metastasis status following tumor signs in 98 lung cancer patients with I - IIIA stage who underwent thoracoscopic lobectomy and lymph node dissection at 108 Military Central Hospital from 5/2017 - 3/2021. Results: Lymph node metastasis rate was 30.6%; the rate of lymph node metastasis to the superior mediastinal region of the upper lobe tumor was 15.2%; the rate of lymph node metastasis to the inferior mediastinal region of the lower lobe tumor was 31.4%. In the tumor diameter ≥ 5 - 7 cm group, the N1 lymph node metastasis accounted for the highest proportion (25.0%), and the N2 lymph node metastasisis rate was 29.6% in the tumor diameter ≥ 3 - 5 cm group. In the tumor invasion group, the N2 lymph node metastasis proportion made up 26.5%. Conclusion: The lymph node metastasis is related to tumor location and tumor size. The tumor invasion tends to be related to lymph node metastasis.
Article Details
Keywords
Phẫu thuật nội soi cắt thùy phổi, Thoracoscopic lobectomy
References
2. Trần Minh Bảo Luân (2018). Đánh giá kết quả điều trị UTPKTBN bằng PTNS cắt thùy phổi và nạo hạch. Trường Đại học Y Dược Thành phố Hồ Chí Minh.
3. Moulla Y., et al. (2019). Predictive risk factors for lymph node metastasis in patients with resected non-small cell lung cancer: a case control study. Journal of Cardiothoracic Surgery; 14(1): 11.
4. Bao F., et al. (2014). Predictive risk factors for lymph node metastasis in patients with small size non-small cell lung cancer. Journal of Thoracic Disease; 6(12): 1697.
5. Nguyễn Khắc Kiểm (2016). Nghiên cứu nạo vét hạch theo bản đồ trong phẫu thuật điều trị UTPKTB Ngiai đoạn I - II - IIIA. Trường Đại học Y Hà Nội.
6. Liang R.B., et al. (2018). Incidence and distribution of lobe-specific mediastinal lymph node metastasis in non-small cell lung cancer: data from 4511 resected cases. Annals of Surgical Oncology; 25(11): 3300-3307.
7. Luo T., Q. Chen, J. Zeng (2020). Analysis of lymph node metastasis in 200 patients with non-small cell lung cancer. Translational Cancer Research; 9(3): 1577-1583.
8. Asamura H., et al. (2000). Where is the boundary between N1 and N2 stations in lung cancer? The Annals of Thoracic Surgery; 70(6): 1839-1846.
9. Bao F., et al. (2014). Segmentectomy or lobectomy for early stage lung cancer: a meta-analysis. European Journal of Cardio-Thoracic Surgery; 46(1): 1-7.
10. Manac’h D., et al. (2001). Visceral pleura invasion by non-small cell lung cancer: an underrated bad prognostic factor. The Annals of Thoracic Surgery; 71(4): 1088-1093.