PHÌ ĐẠI TUYẾN CẬN GIÁP TRÊN SIÊU ÂM Ở BỆNH NHÂN LỌC MÁU CHU KỲ CÓ NỒNG ĐỘ PTH HUYẾT TƯƠNG CAO TẠI BỆNH VIỆN QUÂN Y 103

Abstract

Objectives: To investigate the prevalence of parathyroid gland enlargement detected by ultrasonography and its association with selected clinical and paraclinical characteristics in patients with end-stage kidney disease undergoing maintenance hemodialysis and presenting with elevated plasma parathyroid hormone (PTH) levels (> 300 pg/mL). Methods: A cross-sectional descriptive study without a control group was conducted on 56 hemodialysis patients with plasma PTH levels > 300 pg/mL at Military Hospital 103, from May 2025 to April 2026. Results: The prevalence of parathyroid gland enlargement was 66.1% among maintenance hemodialysis patients with elevated plasma PTH levels. Parathyroid gland enlargement was significantly associated with older age (> 50 years), lower plasma albumin levels, and plasma PTH levels > 600 pg/mL. Multivariable logistic regression analysis demonstrated that lower plasma albumin (OR = 0.765; 95%CI: 0.588 - 0.995; p = 0.046) and higher plasma PTH levels (OR = 1.002; 95%CI: 1.000 - 1.004; p = 0.018) were independently associated with parathyroid gland enlargement. Conclusion: The prevalence of parathyroid gland enlargement was 66.1% among maintenance hemodialysis patients with plasma PTH levels > 300 pg/mL. Parathyroid gland enlargement was associated with older age, lower plasma albumin levels, and higher plasma PTH levels.