NGHIÊN CỨU MỘT SỐ ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG, HÌNH ẢNH SIÊU ÂM DOPPLER VÀ FIBROSCAN Ở BỆNH NHÂN MẮC BỆNH GAN MẠN TÍNH

Abstract

Objectives: To assess some clinical and subclinical characteristics, imaging of  Doppler and Fibroscan  ultrasound in patients  with chronic  liver disease.

Subjects and methods: A prospective, descriptive cross-sectional study on 66 patients diagnosed with chronic hepatitis and treated from September 2021 to September 2022 at Military Hospital 103. The patients were tested on some parameters such as AST, ALT, GGT, platelet, and a FIB4 index. Doppler ultrasound was performed to examine the PV, hepatic artery, RI of the hepatic artery, and Fibroscan ultrasound to assess the degree of fatty liver S0 - S4, stages of fibrosis liver F0 - F4 according to Metavir. Results: The common symptoms in patients with chronic hepatitis were pain (30.3%) and darkening of the skin (30.3%). Most patients had an increase in AST, ALT, and GGT (31.82%, 39.39%, and 39.39%, respectively). The number of patients with a FIB-4 index under 1.45 accounted for the highest rate (54.55%). In Doppler ultrasound, the rate of PV dilation accounted for 10.61%, increased RI of the hepatic artery was 48.48%; in Fibroscan ultrasound, the rate of patients with fatty liver occupied 43.94%, the percentage of F0 - F1 fibrosis occupied the majority (68.18%). Meanwhile, the F4 fibrosis rate was 13.64%. Conclusion: Patients with chronic liver disease should be added to functional liver tests and Doppler and Fibroscan ultrasound to detect RI of hepatic artery fatty liver, fibrosis and cirrhosis.