PHÂN BỐ CÁC CHỦNG VI KHUẨN PHÂN LẬP VÀ KẾT CỤC LÂM SÀNG CỦA BỆNH NHÂN CẤY KHUẨN DƯƠNG TÍNH TẠI TRUNG TÂM HỒI SỨC CẤP CỨU, CHỐNG ĐỘC, BỆNH VIỆN QUÂN Y 103

Abstract

Objectives: To describe the distribution of isolated bacterial strains and its association with clinical outcomes of patients (mortality rate, mechanical ventilation duration, and intensive care unit (ICU) length of stay). Methods: A retrospective, cross-sectional descriptive study was conducted on 781 patients with positive microbiological cultures at the Intensive Care, Emergency and Poison Control Centre, Military Hospital 103, from January to December 2025. Data were analyzed using SPSS 22.0 software via Chi-square and Kruskal-Wallis tests. Results: A. baumannii was the most prevalent strain (27.8%), followed by P. aeruginosa (26.0%); both were predominantly isolated from the respiratory tract (92.6% and 72.4%, respectively). The overall mortality rate was 37.9%, which was highest in the Klebsiella pneumoniae group (53.3%), followed by A. baumannii (36.9%) and P. aeruginosa (31.5%) (p < 0.05). P. aeruginosa infection significantly prolonged the duration of mechanical ventilation (median 22 [14 - 32] days) and ICU stay (median 32 [19 - 48] days). Conclusion: Gram-negative bacilli, particularly P. aeruginosa, A. baumannii, and K. pneumoniae, are the predominant pathogens in the ICU setting, which are significantly associated with increased mortality, prolonged mechanical ventilation, and extended ICU length of stay.