MỐI LIÊN QUAN GIỮA PHÁT TRIỂN THẦN KINH GIAI ĐOẠN 3 TUỔI VỚI NĂNG LỰC HỌC TẬP GIAI ĐOẠN 8 TUỔI Ở NHÓM TRẺ SINH SỐNG XUNG QUANH KHU VỰC Ô NHIỄM DIOXIN

Abstract

Objectives: To assess the relationship between neurodevelopmental indicators at age 3 and learning abilities at age 8 in children living around a dioxin-contaminated area. Methods: A longitudinal cohort study was conducted on 166 pairs of mothers and children living around Da Nang airport from July 2008 to July 2017, who were followed from birth and assessed for neurodevelopment and intellectual ability at different ages. At age 3, neurodevelopmental indicators, including cognition, receptive language, expressive language, fine motor, and gross motor skills, were assessed by Bayley-III. At age 8, a questionnaire of learning difficulties (CLDQ) and mathematical and language (Vietnamese) tests were conducted. Multivariate linear regression analysis was performed to clarify the relationship between neurodevelopmental indicators at age 3 and learning ability at age 8. Results: In boys, neurodevelopmental indicators at age 3 were significantly associated with language learning difficulties and scores in both mathematics and Vietnamese tests at age 8. In girls, although there was no significant association with learning difficulties, there were significant associations with math and Vietnamese scores. Conclusion: The neurodevelopment status of children at age 3 is closely related to intellectual and learning abilities at age 8, especially in boys.