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Issue: Vol. 51 No. 7 (2026): JOURNAL OF MILITARY PHARMACO-MEDICINE No.7 - 2026
Section: Articles
DOI: 10.56535/jmpm.v51i7.2053
Date Published: 28/07/2026
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Nguyen, T. N. M., & Le, T. T. (2026). EVALUATION OF THE EFFECTIVENESS OF A VENTILATOR-ASSOCIATED PNEUMONIA PREVENTION BUNDLE IN PATIENTS WITH INHALATION BURN INJURY. Journal of Military Pharmaco-medicine, 51(7), 152-160. https://doi.org/10.56535/jmpm.v51i7.2053

EVALUATION OF THE EFFECTIVENESS OF A VENTILATOR-ASSOCIATED PNEUMONIA PREVENTION BUNDLE IN PATIENTS WITH INHALATION BURN INJURY

Thai Ngoc Minh Nguyen1,2, , Trung Ton Le1
1 Le Huu Trac National Burn Hospital
2 Vietnam Military Medical University

Main Article Content

Abstract

Objectives: To evaluate the changes in knowledge and the outcomes of implementing a ventilator-associated pneumonia (VAP) prevention bundle in patients with inhalation burn injury. Methods: A cross-sectional descriptive study (survey of 28 nurses) and a before-and-after intervention study with a historical control group were conducted on 67 mechanically ventilated patients with inhalation burn injury (35 retrospective, 32 intervention) at Le Huu Trac National Burn Hospital from January 2022 to June 2024. An 11-component prevention bundle was applied to the intervention group. Results: In the retrospective group, the incidence of VAP was 77.14%. After training, the proportion of nurses with good knowledge increased from 10.71% to 71.43%. The intervention bundle reduced the incidence of VAP to 59.38% (p = 0.117) and shortened the duration of mechanical ventilation from 29.0 ± 2.94 to 14.7 ± 8.96 days (p = 0.028). Multivariate regression analysis confirmed that the prevention bundle was an independent protective factor (OR = 0.04; p = 0.025), while the APACHE II score was an independent risk factor (OR = 3.07; p = 0.002). Conclusion: The 11-component prevention bundle effectively shortened the duration of mechanical ventilation and improved mortality trends. Continued implementation and addressing workforce and supply barriers are necessary.

Keywords

Ventilator‑associated pneumonia, inhalation burn, prevention bundle, nursing, antimicrobial resistance

Article Details

References

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